DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SoxN and Hmgxb4

DIOPT Version :9

Sequence 1:	NP_001260269.1	Gene:	SoxN / 44275	FlyBaseID:	FBgn0029123	Length:	761	Species:	Drosophila melanogaster
Sequence 2:	NP_821136.1	Gene:	Hmgxb4 / 70823	MGIID:	1918073	Length:	594	Species:	Mus musculus

Alignment Length:	270	Identity:	56/270 - (20%)
Similarity:	105/270 - (38%)	Gaps:	40/270 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 QSHLTHSQLSHHNHHHHHMS-----AHIAASQSPNP-------------LSSLQSSMANTLN-GS 90
            ||.|..::..|.:....|.|     .....||.|.|             |...:||.|..|. |.
Mouse   242 QSLLKTARKKHKSSSDSHSSPGPEGCGSDVSQLPEPHSANLDITGLDPILVESESSSAGELEAGE 306

  Fly    91 QVGQQQQQQQQQQSSPLHSSSELSPTQSSIGSHHMTSPVSHQQHTQQQQHGQQQHLGAGSALSSL 155
            .|.....::.:::.....|..:....:.....|..|...|.::|...::||...  |..|::.:|
Mouse   307 LVIDDSYREIKKKKKSKKSKKKKDKDRHKEKRHSRTKRSSAREHGTAREHGLIP--GPASSVPTL 369

  Fly   156 ------TGGSSNNNNNSATANKNQQHADRVKRP-MNAFMVWSRGQRRKMASDNPKMHNSEISKRL 213
                  |.|...........:::::..::.|:. |:|:.|:.:..|..:.:|:|.:...|:||:|
Mouse   370 PLPALHTDGHGEKKKKREDKDRDRERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKL 434

  Fly   214 GAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKTKEKYPMGGL-MPGQTVGG 277
            ...||.|.|.:|..:..:|:.|           :::..:...|..|.|.....|.: :...:||.
Mouse   435 AEVWKQLPEKDKLIWKQKAQYL-----------QHKQNKAEATTVKRKASSAEGSMKVRASSVGV 488

  Fly   278 GAPGEPVTPT 287
            .:|.:...||
Mouse   489 LSPQKKSPPT 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	18/71 (25%)
Hmgxb4	NP_821136.1	DUF4171	107..225	CDD:290491
Hmgxb4	NP_821136.1	HMG-box	400..463	CDD:238037	18/73 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1641977at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010