Protein Alignment SoxN and SOX15

DIOPT Version :9

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_008873.1
• Gene: SOX15 / 6665
• HGNCID: 11196
• Length: 233
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 102/292 - (34%)
• Similarity: 122/292 - (41%)
• Gaps: 113/292 - (38%)

  Fly   148 AGSALSSLTGGSSNNNNNSATANKNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKR 212
            |.:|.:|.:.|........:.|.......::||||||||||||..|||:||..||||||||||||
Human    18 AATAAASSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKR 82

  Fly   213 LGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKTKEKYPMGGLMP---GQT 274
            ||||||.|.|.|||||::|||||||.|::::||||||||||.|:          .|..|   ||.
Human    83 LGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRKAKS----------SGAGPSRCGQG 137

  Fly   275 VGGGAPGEPVTPTRVQGQPGQNQSLNGSGGSAAAAAAAAAAAAQQARQDMYQMNAPN---GYMPN 336
            .|..|.|.|               |.|.|                     |....|:   ||.|
Human   138 RGNLASGGP---------------LWGPG---------------------YATTQPSRGFGYRP- 165

  Fly   337 GYMMHADPAGAAAYQTSYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPSPY 401
                       .:|.|:|:                             ...||||..:..:|||
Human   166 -----------PSYSTAYL-----------------------------PGSYGSSHCKLEAPSP- 189

  Fly   402 GGSSLQQQ-----------------PGSPTPY 416
              .||.|.                 |||||||
Human   190 --CSLPQSDPRLQGELLPTYTHYLPPGSPTPY 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	54/70 (77%)
SOX15	NP_008873.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48		5/29 (17%)
		Required to promote HAND1 transcriptional activator activity. /evidence=ECO:0000250|UniProtKB:P43267	1..47		5/28 (18%)
		SOX-TCF_HMG-box	48..119	CDD:238684	54/70 (77%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	113..153		22/85 (26%)
		Interaction with FHL3. /evidence=ECO:0000250|UniProtKB:P43267	138..183		19/121 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	208..233		7/12 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910