Protein Alignment SoxN and SOX1

DIOPT Version :9

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_005977.2
• Gene: SOX1 / 6656
• HGNCID: 11189
• Length: 391
• Species: Homo sapiens
• Alignment Length: 386
• Identity: 162/386 - (41%)
• Similarity: 191/386 - (49%)
• Gaps: 73/386 - (18%)

  Fly   147 GAGSALSSLTGGSSNNNNNSATANKNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISK 211
            |||..     ||..........|..||   ||||||||||||||||||||||.:|||||||||||
Human    27 GAGGG-----GGGGGGGGGGGGAKANQ---DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISK 83

  Fly   212 RLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKTKEKYPM-GGLMPGQTV 275
            ||||:||.:||:||||||||||||||:|||||||||||||||||||.| |:||.: |||:.....
Human    84 RLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLK-KDKYSLAGGLLAAGAG 147

  Fly   276 GGGAP---------GEPVTPTRVQGQPGQ--------NQSLNGSGGSAAAAAAAAAAAAQQARQD 323
            ||||.         |......|::...|.        |...||:...:.||||||||..|:|:..
Human   148 GGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLA 212

  Fly   324 MYQMNAPNGYMPNGYMMHADPAGAAAYQTSYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQTSPY 388
            ..|.....|..|:.:..|..|....|:..:....|    |||||.:      .|..:|..|  .|
Human   213 YGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMH----RYDMGAL------QYSPISNSQ--GY 265

  Fly   389 GSSLQQPGSPSPYGGSSLQQQPGSPTPYG---------GGGGGGGQVSCQSHSPSDSS------- 437
            .|:     |||.|||          .|||         ||......|:..:.:.:.||
Human   266 MSA-----SPSGYGG----------LPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALG 315

  Fly   438 --IKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAAAAAAAAAGGGELNHLMNMY 496
              :|||| |.||.|.|.:......:...|...|..|......|||||||....|:.|...|
Human   316 SLVKSEP-SGSPPAPAHSRAPCPGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSLPQHY 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	63/70 (90%)
SOX1	NP_005977.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		10/32 (31%)
		SOX-TCF_HMG-box	50..121	CDD:238684	63/70 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..249		7/38 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159968
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X927
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.840