DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SoxN and hmgxb4a

DIOPT Version :9

Sequence 1:	NP_001260269.1	Gene:	SoxN / 44275	FlyBaseID:	FBgn0029123	Length:	761	Species:	Drosophila melanogaster
Sequence 2:	XP_005163967.1	Gene:	hmgxb4a / 559742	ZFINID:	ZDB-GENE-070912-675	Length:	632	Species:	Danio rerio

Alignment Length:	214	Identity:	56/214 - (26%)
Similarity:	92/214 - (42%)	Gaps:	46/214 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 GSQVGQQQQQQQQQQS-SPLHSSSELSPTQSSIGSHHMTSPVSHQQHTQQQQHGQQQHLGAGSAL 152
            |...|::..|..|.:| |..||||..|   ||.|.:.|..|.|..||...:..|:::
Zfish   367 GGSGGKKSSQGDQPRSHSHTHSSSNHS---SSGGMYPMAPPTSSHQHQSIELIGEKK-------- 420

  Fly   153 SSLTGGSSNNNNNSATANKNQQHADR------VKRPMNAFMVWSRGQRRKMASDNPKMHNSEISK 211
                            ..|.::..|:      .|:.|.|:.|:.:..|..:.::.|.:...|:||
Zfish   421 ----------------KKKEEKERDKHDKDKPKKKNMTAYQVFCKEYRVNINAEQPGLVFGELSK 469

  Fly   212 RLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKTKEK-----YPMG-GLM 270
            :|...||.|.|.:|..:..:|:.|:  | |::.......:|||.|.:.:|.|     :.:| ||.
Zfish   470 KLAEVWKQLPEKDKLVWRQKAQYLQ--H-KQNKAEAMTVKRKTLTTSDSKSKGSSKAFSLGSGLA 531

  Fly   271 PGQTVGGGAPGEPVTPTRV 289
            |   .|..:.|..::|.||
Zfish   532 P---QGRSSLGMSLSPARV 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	19/76 (25%)
hmgxb4a	XP_005163967.1	DUF4171	121..262	CDD:290491
hmgxb4a	XP_005163967.1	HMG-box	441..500	CDD:238037	18/61 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1641977at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010