Protein Alignment SoxN and SOX6

DIOPT Version :9

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001139291.2
• Gene: SOX6 / 55553
• HGNCID: 16421
• Length: 828
• Species: Homo sapiens
• Alignment Length: 550
• Identity: 123/550 - (22%)
• Similarity: 191/550 - (34%)
• Gaps: 216/550 - (39%)

  Fly    30 AASPYSALAPLMNLGQSHLTHSQLSH---------------------HNHHHHHM----SAHIAA 69
            ||:..|.|:|| .|.:.|::|.|::.                     |:::|..:    :|.:|:
Human   313 AAAAASGLSPL-QLQKGHVSHPQINQRLKGLSDRFGRNLDTFEHGGGHSYNHKQIEQLYAAQLAS 376

  Fly    70 SQ-SPN---PLSSLQSSMANTLNGSQVGQQQ-------QQQQQQQSSPLHSSSE----------L 113
            .| ||.   |.:....:.|.|::.:.:..::       |.:.:..:.||:.||.          .
Human   377 MQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPT 441

  Fly   114 SPTQSSIGSHHMTSPVS------------------------------------------------ 130
            ||||:...: ..||||:
Human   442 SPTQNLFPA-SKTSPVNLPNKSSIPSPIGGSLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARK 505

  Fly   131 HQQHTQQQQHGQQQHLGAGSALSSLTG-----------------------GSSNNNNN------- 165
            .::..|::|..||.| |....|||:..                       |.||.:..
Human   506 MREQIQREQQQQQPH-GVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVID 569

  Fly   166 -------------SATANKNQQH-------------------------ADRVKRPMNAFMVWSRG 192
                         :.:|.|.||:                         ...:||||||||||::.
Human   570 LTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKD 634

  Fly   193 QRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTL 257
            :|||:....|.||||.|||.||::||.:|..||:|:.:|..||..:|::::|:|||:||.| :|.
Human   635 ERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPK-RTC 698

  Fly   258 TKTKEKYPMG---GLMPGQ--------TVGGGAPGEPVTPTRVQGQPGQNQSLNGSGGSAAAAAA 311
            ....:|..:|   .||..:        || |..|..|:|.......||             |...
Human   699 IVDGKKLRIGEYKQLMRSRRQEMRQFFTV-GQQPQIPITTGTGVVYPG-------------AITM 749

  Fly   312 AAAAAAQQARQDMYQMNA-PNGYMP---NGYMMHADPAGAAAYQTSYMGQHYAAQRYDMGHMYNN 372
            |....:.|...|....:| |...:|   :.|.|..|....|                  |:...|
Human   750 ATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLA------------------GNEMIN 796

  Fly   373 G---YAMYQTVSGGQTSPYGSSLQQPGSPS 399
            |   ..||........|.|.|..:.|.:.|
Human   797 GEDEMEMYDDYEDDPKSDYSSENEAPEAVS 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	36/70 (51%)
SOX6	NP_001139291.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..51
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	380..470		18/90 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	753..828		18/91 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810