DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SoxN and hbp1

DIOPT Version :9

Sequence 1:	NP_001260269.1	Gene:	SoxN / 44275	FlyBaseID:	FBgn0029123	Length:	761	Species:	Drosophila melanogaster
Sequence 2:	NP_001019602.2	Gene:	hbp1 / 554137	ZFINID:	ZDB-GENE-050522-414	Length:	494	Species:	Danio rerio

Alignment Length:	177	Identity:	50/177 - (28%)
Similarity:	71/177 - (40%)	Gaps:	46/177 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 LQSSMANTLNGSQVGQQQQQQQQQQSSPLHSSSELSP---TQSSIG-SHHMTSPVSHQQHTQQQQ 139
            |.||....|  |.:|:|::..|.       |...:||   ...::| :||.:|..|.:.|
Zfish   352 LDSSAVYVL--SSMGRQRRASQS-------SGGAVSPDCDKLEALGFTHHSSSSKSQRSH----- 402

  Fly   140 HGQQQHLGAGSALSSLTGGSSNNNNNSATANKNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKM 204
                            ..|||     .||..|       .||||||||::::..|.:.....|..
Zfish   403 ----------------ASGSS-----GATPTK-------CKRPMNAFMLFAKKYRVEYTQMYPGK 439

  Fly   205 HNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPR 251
            .|..||..||.:||.:...|:|.:..|||.|.....:.:||...|.|
Zfish   440 DNRAISVILGDKWKKMKNEERRMYTMEAKALAEEQKRLNPDCWKRKR 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	25/70 (36%)
hbp1	NP_001019602.2	AXH	210..328	CDD:285689
hbp1	NP_001019602.2	SOX-TCF_HMG-box	413..484	CDD:238684	26/77 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1641977at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010