Protein Alignment SoxN and cic

DIOPT Version :10

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001262755.1
• Gene: cic / 53560
• FlyBaseID: FBgn0262582
• Length: 2150
• Species: Drosophila melanogaster
• Alignment Length: 863
• Identity: 191/863 - (22%)
• Similarity: 297/863 - (34%)
• Gaps: 266/863 - (30%)

  Fly    13 LHATMPPHHTSAALHGHAASPYSALAPLMNLGQSHLTHSQLSHHNHHHHHMSAHIA--ASQSPNP 75
            |...:||  |:.:.| ...:|.|..|.:.::.|..:...  :.:|.....:..|:.  :..||.|
  Fly   988 LSVPLPP--TTVSFH-QPNTPTSTAASVASMSQDKMLAK--NGYNAPWFKLLPHMTPMSKASPAP 1047

  Fly    76 LSSLQSSMANTLN---------GSQVGQQQQQQQQQQSSPL----HSSSEL-------------- 113
            ::...::.|::.|         ..|:.||||.||||||.|.    |:::.|
  Fly  1048 VTPTLTTSASSYNVVMMQQQQQHQQLQQQQQLQQQQQSPPQMPLNHNNNHLIVSAPLSSPGKPLN 1112

  Fly   114 -SPTQSSIGSHHMTSPVSHQQHTQQQQHGQQQHLGAGSALSSLTGGSSNNNNNSA-----TANKN 172
             |...:.:.:....:.|::|:..|||:....| |......::..|.|:|:...:|     |.|.|
  Fly  1113 CSMNDAKVAAAAAAAAVANQRQKQQQEEPDDQ-LDDDVFETTTPGISANSKKQTAAMRLPTHNSN 1176

  Fly   173 -------------------------------------QQHA------------DRVKRPMNAFMV 188
                                                 ||.|            .:::|||||||:
  Fly  1177 IRKLEECHDDGAAGAPATSAAKRRSQSLSALQQQQQQQQQAGAAGTAAGQPANKKIRRPMNAFMI 1241

  Fly   189 WSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKY--RPR 251
            :|:..|:.:...:|...|..:||.||..|..|...:|..:.:.|..::..|.|.||::|:  :.|
  Fly  1242 FSKKHRKMVHKKHPNQDNRTVSKILGEWWYALKPEQKAQYHELASSVKDAHFKLHPEWKWCSKDR 1306

  Fly   252 RKTKTLTKTKEKYPMGGLMPGQTVGGGAPGEPVTPTRVQGQPGQNQSLNGS--GGSAAAAAAAAA 314
            ||:.|.|.|.     ||...|....|.|....|:   |.|.......:..|  |||.:......:
  Fly  1307 RKSSTSTATP-----GGKASGAAGTGDAKQRLVS---VDGSDSLEHDMCPSTPGGSGSCGGQGIS 1363

  Fly   315 AAAQ----QARQDMYQM---NAP-------NGYMPNGYMMHAD-PAG----------AAAYQT-- 352
            :..|    ....|.|..   .||       ||   ||.:|..: |:.          ....||
  Fly  1364 SDLQGDIIPLTIDNYNSTCDEAPTTISMKGNG---NGKLMKNELPSDEDEQMLVVEEEQQQQTVK 1425

  Fly   353 --------------------SYMGQH-YAAQRYDMGHMYN--NGYAM-YQTVSGGQTS------- 386
                                .|..|. .|.||....|..:  ||.|: ...:|||:..
  Fly  1426 KIDLHCRERVNDSDMDDTPFDYRKQQPEANQRSAEEHSTSGANGQAINAPPLSGGEREITLKPKA 1490

  Fly   387 ------------PYG--SSLQQPGSP-SPYG-------GSSLQQQPGSPTPYGGGGGGGGQVSCQ 429
                        ||.  |...|..|| :|.|       |.:.:..|.||.  |.||......|.|
  Fly  1491 IKAHPVLESNMLPYTQMSIYTQYTSPKNPIGVTPFQPTGGAFKSMPISPK--GSGGKPEDAGSLQ 1553

  Fly   430 SHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAAAAAAAAAGGGELNHLMN 494
            :|...: .||.||    ||...|||              .|.:|:.....:|.....|.:..:.|
  Fly  1554 AHIKQE-DIKQEP----PSPYKLNN--------------GSGSASGGGVVSAPPPNSGSVGAIFN 1599

  Fly   495 MYHLP------DEQRHL-LHYQTDSP-DLQQQHQ----------------SMQQQQQHLPQQHL- 534
             :::|      .:|.|. :|:...|| ||:..||                ::.......|.|.:
  Fly  1600 -FNVPTATALSQKQFHYPMHHPHRSPTDLRAAHQACVPSSPAGMGLGHAANIATPPASAPAQIMG 1663

  Fly   535 ---SQQHQQIPQQH-HTMQQQQQQ---HHLQHQQSLRAMAPLAHMXEMASAYGAAGSSVSVSPPL 592
               :.|.......| :|:.|:..|   ..|:|.| |.|.||..:.....:...:....||..|.:
  Fly  1664 GGPASQKMFFAMTHPYTLLQRSHQPGTPSLEHLQ-LDAFAPGGYTLRNHNGLSSLPPPVSAQPTM 1727

  Fly   593 -----------------PPY--MPTAPQQQQQQQQQQQQLLNGRPSPTASGSSGGRSSAHSSGHT 638
                             |.|  ||:.|       :....|::..|.....|...|.:||.:||..
  Fly  1728 LLHGYPPSHGVEPPARSPSYKSMPSTP-------KSATYLMSAPPERGMDGGMSGCASAAASGGD 1785

  Fly   639 AAHSPALAAAYQLTPSAA 656
            .:...|....:.|.|:.|
  Fly  1786 ESDIDADGQQFILAPTPA 1803

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	HMG-box_SoxB	177..252	CDD:438790	24/76 (32%)
cic	NP_001262755.1	DUF4819	349..432	CDD:465014
		HMG-box_CIC-like	1231..1308	CDD:438806	25/76 (33%)