Protein Alignment SoxN and Sox2

DIOPT Version :10

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001102651.1
• Gene: Sox2 / 499593
• RGDID: 1565646
• Length: 319
• Species: Rattus norvegicus
• Alignment Length: 396
• Identity: 150/396 - (37%)
• Similarity: 183/396 - (46%)
• Gaps: 112/396 - (28%)

  Fly   131 HQQHTQQQQHGQQQHLGAGSALSSLTGGSSNNNNNSATANKNQQHADRVKRPMNAFMVWSRGQRR 195
            :...|:.:..|.||..|.        ||...|...:||....:...|||||||||||||||||||
  Rat     3 NMMETELKPPGPQQASGG--------GGGGGNATAAATGGNQKNSPDRVKRPMNAFMVWSRGQRR 59

  Fly   196 KMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKT 260
            |||.:|||||||||||||||:||.|||:||||||||||||||:|||||||||||||||||||.|
  Rat    60 KMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMK- 123

  Fly   261 KEKYPM-GGLMPGQTVGGGAPGEPVTPTRVQGQPGQNQSLNGSGGSAAAAAAAAAAAAQQARQDM 324
            |:||.: |||:                     .||.|...:|.|      ..|...|....|.|.
  Rat   124 KDKYTLPGGLL---------------------APGGNSMASGVG------VGAGLGAGVNQRMDS 161

  Fly   325 YQMNAPNGYMPNGYMMHADPAGAAAYQTSYMGQHYAAQ-----RYDMGHMYNNGYAMYQTVSGGQ 384
            |.  ..||:....|.|..:..|..  |...:..|.|||     |||:..:..|.....||...|
  Rat   162 YA--HMNGWSNGSYSMMQEQLGYP--QHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNG- 221

  Fly   385 TSP-YGSSLQQPGSPSPYGGSSLQQQPGSPTPYGGGGGGGGQVSCQSHSPSDSSIKSEPVSPSPS 448
             || |..|..|.|:|    |.:|              |..|.|           :||| .|.||.
  Rat   222 -SPTYSMSYSQQGTP----GMAL--------------GSMGSV-----------VKSE-ASSSPP 255

  Fly   449 AIALNNNNNINNNHIMKREYSSAAAAAAAAAAAAAAGGGELNHLMNMY----HLPD----EQRHL 505
            .:.                 ||:.:.|...|       |:|..:::||    .:|:    .:.|:
  Rat   256 VVT-----------------SSSHSRAPCQA-------GDLRDMISMYLPGAEVPEPAAPSRLHM 296

  Fly   506 L-HYQT 510
            . |||:
  Rat   297 AQHYQS 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	HMG-box_SoxB	177..252	CDD:438790	68/74 (92%)
Sox2	NP_001102651.1	HMG-box_SoxB	41..120	CDD:438790	72/78 (92%)
		SOXp	112..202	CDD:463537	37/121 (31%)