Protein Alignment SoxN and Sox21b

DIOPT Version :10

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: XP_061509694.1
• Gene: Sox21b / 4577582
• VectorBaseID: AGAMI1_014325
• Length: 529
• Species: Anopheles gambiae
• Alignment Length: 610
• Identity: 185/610 - (30%)
• Similarity: 227/610 - (37%)
• Gaps: 219/610 - (35%)

  Fly   123 HHMTSPVSHQQHTQQQQ-------HGQQQHLGAGSALSS-------------LTGGSSNNNNNSA 167
            |.::.|.|.....|...       |.|..|..:.:||.:             |.|.:.|.....|
Mosquito    68 HSLSIPTSQSLSNQSSHALNSLGLHSQNLHASSVNALHNSQTTNLHQNVSGLLNGAAGNGLLGQA 132

  Fly   168 TANKNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEA 232
            ...|..:  :.:||||||||||||.||||:|.||||||||||||||||:||.|:|.|||||||||
Mosquito   133 MLKKPAE--EHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEDEKRPFIDEA 195

  Fly   233 KRLRAVHMKEHPDYKYRPRRKTKTLTKTKEKYPM-------GGLMPGQTVGGGAPGEP--VTPTR 288
            |||||:|||||||||||||||.|.:.:....|||       ..|..|.|....|||.|  :....
Mosquito   196 KRLRAMHMKEHPDYKYRPRRKPKPIRRDGYPYPMTYPSVPVDALRAGITPSYFAPGAPYHLGSHL 260

  Fly   289 VQGQPGQNQSLNGS---------GGSAAAAAAAAAAAAQQARQDMYQMNA---PNGYMPNGYM-- 339
            .|..|...||...|         ..||....|||.|....|:......:|   |...:...|.
Mosquito   261 SQASPPTTQSSISSQMDVSKFALDRSAYLNTAAAGALYDTAKSQTNPYSAYLDPTSVLTKAYFDS 325

  Fly   340 -MHADPAGAAAYQTSYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPSPYGG 403
             |:.|.|.|||        :||   :|:..:|.       |.:..|....|||     |.:..|.
Mosquito   326 KMYQDRAQAAA--------NYA---FDISKIYG-------TTAQQQQQQLGSS-----SSTSSGS 367

  Fly   404 SSLQQQPGSPTPYGGGGGGGGQVSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREY 468
            ||.|||
Mosquito   368 SSQQQQ----------------------------------------------------------- 373

  Fly   469 SSAAAAAAAAAAAAAAGGGELNHLMNMYHLPDEQRHLLHYQTDSPDLQQQHQSMQQQQQHLPQQH 533
                                                           |||||..||||||  |||
Mosquito   374 -----------------------------------------------QQQHQQQQQQQQH--QQH 389

  Fly   534 LSQQHQQIPQQHHTMQQQQQQHHLQHQQSLRAMAPLAHMXEMASAYGAAGSSVSVSPPLPPYMPT 598
              |||||     |  |.||..|||.|        ||.|. ::.:  |||...:......|.....
Mosquito   390 --QQHQQ-----H--QLQQSPHHLHH--------PLHHQHQLQN--GAASGGLDERESTPQLGDV 435

  Fly   599 APQQQQQQQQQQQQLLNGRPSPTAS------GSSGGRSSAHSSGHTAAHSPALAAAYQLTPSAAT 657
            .|..:.|..:.    |.|.|..:.|      |..||.|:|.:||           .||.  |||.
Mosquito   436 TPDIKPQIVEP----LEGSPLHSHSYGVGLLGVGGGASAATTSG-----------LYQY--SAAA 483

  Fly   658 SSATSAAAAAATAAAVAAAAAAGSS 682
            .:|:.|||..::.....::...|.:
Mosquito   484 MAASQAAANGSSGGGGGSSGGGGGN 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	HMG-box_SoxB	177..252	CDD:438790	63/74 (85%)
Sox21b	XP_061509694.1	None