Protein Alignment SoxN and sox2

DIOPT Version :9

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_998869.1
• Gene: sox2 / 407873
• XenbaseID: XB-GENE-484553
• Length: 311
• Species: Xenopus tropicalis
• Alignment Length: 427
• Identity: 154/427 - (36%)
• Similarity: 189/427 - (44%)
• Gaps: 145/427 - (33%)

  Fly   159 SSNNNNNSATANKNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSES 223
            :|..|:||.:.|:::...||||||||||||||||||||||.:|||||||||||||||:||.|||:
 Frog    17 ASGGNSNSGSNNQSKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEA 81

  Fly   224 EKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKTKEKYPM-GGLMPGQTVGGGAPGEPVTPT 287
            ||||||||||||||:|||||||||||||||||||.| |:||.: |||:
 Frog    82 EKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMK-KDKYTLPGGLL----------------- 128

  Fly   288 RVQGQPGQNQSLNGSGGSAAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAGAAAYQT 352
                .||.|...:|.|.|..|..        ..|.|.|.  ..||:...||.|..:..|..  |.
 Frog   129 ----APGANPMTSGVGASLGAGV--------NQRMDTYA--HMNGWTNGGYGMMQEQLGYP--QH 177

  Fly   353 SYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQT----SP-YGSSLQQPGSPSPYGGSSLQQQPGS 412
            ..:..|.|.|...| |.|:.....|.::|..||    || |..|..|.|:|    |.||
 Frog   178 PGLSAHNAPQMQPM-HRYDVSALQYNSMSSSQTYMNGSPTYSMSYSQQGAP----GMSL------ 231

  Fly   413 PTPYGGGGGGGGQVSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAA 477
                    |..|.|           :|||. |.||..:.                 ||:.:.|..
 Frog   232 --------GSMGSV-----------VKSES-SSSPPVVT-----------------SSSHSRAPC 259

  Fly   478 AAAAAAAGGGELNHLMNMYHLPDEQRHLLHYQTDSPDLQQQHQSMQQQQQHLPQQHLSQQHQQIP 542
            .|       |:|..:::|| ||.                                      .::|
 Frog   260 QA-------GDLRDMISMY-LPG--------------------------------------AEVP 278

  Fly   543 QQHHTMQQQQQQHHLQHQQS-------LRAMAPLAHM 572
            :.    ..|.:.|..||.||       :....||:||
 Frog   279 EP----AAQSRLHMSQHYQSASVAGTAINGTLPLSHM 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	64/70 (91%)
sox2	NP_998869.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..40		9/22 (41%)
		SOX-TCF_HMG-box	36..107	CDD:238684	64/70 (91%)
		SOXp	106..194	CDD:372055	39/122 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	232..259		12/55 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5512
SonicParanoid	1	1.000	-	-		X927
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.040