Protein Alignment SoxN and Sox21b

DIOPT Version :9

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 594
• Identity: 197/594 - (33%)
• Similarity: 243/594 - (40%)
• Gaps: 196/594 - (32%)

  Fly    20 HH---TSAALHGHAASPYSALAPLMNLGQSHLTH-SQLS-HHNHHHHHMSAHIAASQSPNPLSSL 79
            ||   .:||:|........:   ...||.||..| .||| :|.|||.|.|.........:|.||
  Fly    31 HHLGQLAAAVHQQQQQQQQS---DQGLGHSHHLHGQQLSLNHQHHHPHQSPQHQQQHQHHPCSS- 91

  Fly    80 QSSMANTLNGSQVG-------------------QQQQQ----QQQQQSSPLHSSSELSPTQSSIG 121
                 |:.|||..|                   |..|.    ||||.|.|        |..||..
  Fly    92 -----NSSNGSPNGSTGLGLHPHSALHLAHHHSQLHQHHPAGQQQQHSQP--------PVSSSST 143

  Fly   122 SHHMTS-PVSHQQHTQQQQHGQQQHLGAGSA--LSSLTGGSSN---------------------- 161
            |||..| .:|||.|:    :|..| ||.|||  ..|:.||::|
  Fly   144 SHHSQSQALSHQTHS----NGSSQ-LGGGSASGAGSVAGGAANSHHSAPASSSVMAAAAAAHLHH 203

  Fly   162 ------------------NNNNSA------------TANKNQQHADRVKRPMNAFMVWSRGQRRK 196
                              |:.:||            |..:|::|   :||||||||||||.||||
  Fly   204 NSQASPISNLHQNMGSLMNSGSSASDVFFSLMIQNTTKRQNEEH---IKRPMNAFMVWSRLQRRK 265

  Fly   197 MASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKTK 261
            :|.||||||||||||||||:||.|:|.||||||||||||||:|||||||||||||||.|.|.:..
  Fly   266 IAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKALRRDG 330

  Fly   262 EKYPM----------------GGLMPGQTVG----GGAPGEPVTPTRVQGQPGQNQSLNGSGGSA 306
            ..|||                |...||.|..    |...|:..|||..|.      :|:|.....
  Fly   331 YPYPMPYPSVPVEALRAGITPGYFAPGPTAAAYHLGSHLGQTSTPTTTQA------TLSGQMDKF 389

  Fly   307 AAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAG-AAAYQTSYMGQHYAAQ-RYDMGHM 369
            |...::..:.:.||               :.|..:.||:. ..||..|.|.|..||. .:|:..:
  Fly   390 ALERSSYLSNSSQA---------------SAYSAYLDPSVLTKAYFDSKMYQDRAANYAFDISKI 439

  Fly   370 YNNGYAMYQTVSGGQTSPYGSSLQQPGSPSPYGGSSLQQQPGSPTPYGGGGGGGGQVSCQSHSPS 434
            |           |.|........||...      ...|||........||||.||..|..||:.:
  Fly   440 Y-----------GAQQHAAAHHQQQQQQ------QQQQQQQQQQLLLSGGGGSGGGGSASSHNNN 487

  Fly   435 DSS-------------IKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAA--------AAA 478
            .||             ::|:|...|||.:.|:...       ..::|....|||        ||.
  Fly   488 SSSGLDDRDATPQLEAVESKPHLHSPSDVGLDYAQ-------YAQQYGGQLAAAAGGAVGGGAAG 545

  Fly   479 AAAAAAGGG 487
            ||..:||||
  Fly   546 AAGGSAGGG 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	60/70 (86%)
Sox21b	NP_001261829.1	SOX-TCF_HMG-box	247..318	CDD:238684	61/73 (84%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451315
Domainoid	1	1.000	49	1.000	Domainoid score	I4418
eggNOG	1	0.900	-	-		E1_KOG0527
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I3128
Isobase	1	0.950	-	0	Normalized mean entropy	S1275
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.840