Protein Alignment SoxN and Sox14

DIOPT Version :9

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001286801.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Alignment Length: 729
• Identity: 163/729 - (22%)
• Similarity: 252/729 - (34%)
• Gaps: 247/729 - (33%)

  Fly    70 SQSPNPLSSLQSSMANTLNGSQVGQQQQQQQ---------QQQSSPLHSSSELSPTQSSIGSHHM 125
            |.||:|.||...:.|.|     .|.|:.|.|         ...|:|:.:::..:|......|.|
  Fly    57 SPSPSPASSPSPAPAQT-----PGAQKTQSQAAITHPAAVASPSAPVAAAAPKTPKTPEPRSTH- 115

  Fly   126 TSPVSHQQH-----TQQQQHGQQ--QHLGAGSAL------SSLTGGSSNNNNNSAT----ANKNQ 173
            |...:|.||     .:.:..|::  .|.|....|      |||..||:....||:|    |.:.:
  Fly   116 THTHTHSQHFSPPPRESEMDGERSPSHSGHEMTLSMDGIDSSLVFGSARVPVNSSTPYSDATRTK 180

  Fly   174 QHA-DRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRA 237
            :|: ..:|||||||||||:.:|||:....|.:||:||||.||.:|:.||:.:|:|:|.||::||.
  Fly   181 KHSPGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQLLSKDDKQPYIIEAEKLRK 245

  Fly   238 VHMKEHPDYKYRPRRKTKTLTKTKEKYPMGGLMPGQTVGGGAPGEPVTPTRVQGQPGQNQSLN-- 300
            :||.|:|:|||||::|       :.:.| |.|.|.|...|.......|        ..|.||.
  Fly   246 LHMIEYPNYKYRPQKK-------QTRSP-GSLKPNQDADGCEARNDTT--------NNNNSLTTL 294

  Fly   301 --------GSGGSAAAAAAAAAAAAQQARQD----------------MYQMNAPNGYMPNGYMMH 341
                    |.....:.:...:.:|:::.|.|                ..|:|:.:..:|:
  Fly   295 AINGTTTAGRKSKRSTSTCQSGSASKRLRNDSGDTSSKPKYEVKMESAEQLNSADIILPS----- 354

  Fly   342 ADPAGAAAYQTSYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPSPY-GGSS 405
            ||  ...:||:|                   .|....|:|.....   ..|....|..|. ...:
  Fly   355 AD--NLISYQSS-------------------EYLPLSTLSNADCD---EKLHSELSSGPLESREN 395

  Fly   406 LQQQPGSPTPYGGGGGGGGQVSCQS-----HSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMK 465
            |.:......|...||....|:...|     |:.||           |:|..::|.::|  :.|..
  Fly   396 LSEVVNRFLPLFLGGNEDSQLGVSSLTQSQHNQSD-----------PTAGLMDNISDI--SPIND 447

  Fly   466 REYSSAAAAAAAAAAAAAAGGGELNHLMNMYHLPDEQRHLLHY-----QTDSPDLQQQHQSMQQQ 525
            ||                             .|.:|....|.|     .:|...|:.:..|:..:
  Fly   448 RE-----------------------------ELTEEVMRYLPYLEVNPSSDGLTLKVESSSLLGK 483

  Fly   526 QQHLPQQHLSQQHQQIPQQHHTMQQQQQQHHLQHQQSLRAMAPLAHMXEMASAYGAAGSSVSVSP 590
            ..:.|          :......:......|...||
  Fly   484 PLNEP----------VFDSEDNIVNDANLHSASHQ------------------------------ 508

  Fly   591 PLPPYMPTAPQQQQQQQQQQQQLLNGRPSPTASGSSGGRSSAHS--------------------- 634
             :|||:|.:                   ....:...||.||:|.
  Fly   509 -IPPYVPDS-------------------HDCFAEDCGGDSSSHQVEFEVVRPQTVTMTMTCTLPY 553

  Fly   635 SGHTAAHSPALAAAYQLTPSAATSSATSAAAAAATAAAVAAAAAAGSSF----AASASMLDMQQQ 695
            .|..|.|:...|..:...||||..|..|    ..|.:........||||    |..::....||.
  Fly   554 GGPDAGHTTFQADDFNAIPSAAEDSECS----ILTTSNSPQIGFNGSSFVEADAIGSTCTYAQQD 614

  Fly   696 HLEEQ-QQHHHLHY 708
            :.... :.|:.|:|
  Fly   615 YTGSVIETHNDLNY 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	39/70 (56%)
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684	39/70 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451311
Domainoid	1	1.000	49	1.000	Domainoid score	I4418
eggNOG	1	0.900	-	-		E1_KOG0527
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1275
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.790