Protein Alignment SoxN and Sox17

DIOPT Version :10

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001101372.1
• Gene: Sox17 / 312936
• RGDID: 1305371
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 371
• Identity: 108/371 - (29%)
• Similarity: 158/371 - (42%)
• Gaps: 93/371 - (25%)

  Fly   125 MTSP-VSHQQHTQQQQHGQQQHLGAG-------SALSSL-----------TGGSSNNNNNSATAN 170
            |:|| ..:....|.|....|..:.||       .:||||           :.|:....::.|.|.
  Rat     1 MSSPDAGYASDDQSQPRSAQPAVMAGLGPCPWAESLSSLGDVKVKGEVVASSGAPAGTSSRAKAE 65

  Fly   171 KNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRL 235
                  .|::|||||||||::.:|:::|..||.:||:|:||.||..||.|:.:|||||::||:||
  Rat    66 ------SRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERL 124

  Fly   236 RAVHMKEHPDYKYRPRRK--TKTLTKTKEKY-------------PMGG--LMPGQTVGGGAPGEP 283
            |..||::||:|||||||:  .|.:.:.:..:             |.||  .|.|..:....||.|
  Rat   125 RVQHMQDHPNYKYRPRRRKQVKRMKRVEGGFLHALAEPQAGALGPEGGRVAMDGLGLPFPEPGYP 189

  Fly   284 VTPTRVQGQPGQN-QSLNGSGGSAAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAGA 347
            ..|..:....|.: :...|.|..|.               |.|.:..|:....:|  :..|||..
  Rat   190 AGPPLMSPHMGAHYRDCQGLGAPAL---------------DGYPLPTPDTSPLDG--VEQDPAFF 237

  Fly   348 AAYQTSYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQ----TSPYGSSLQQPGSPSP-------Y 401
            ||   ...|...||..|....:  :.||:....|.|.    ..|.||::  ||..:|       |
  Rat   238 AA---PLPGDCPAAGAYTYAQV--SDYAVPAEPSAGPMRVGPDPSGSAM--PGILAPPSALHLYY 295

  Fly   402 GGSSLQQQPGSPTPYGGGGGGGGQVSCQSHSPSDSSIKSEPVSPSP 447
            |..      |||....|.|         .|:.....::.:|..|.|
  Rat   296 GAM------GSPAASAGRG---------FHAQPQQPLQPQPPPPPP 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	HMG-box_SoxB	177..252	CDD:438790	43/74 (58%)
Sox17	NP_001101372.1	HMG-box_SoxF_SOX17	62..142	CDD:438850	46/85 (54%)
		Sox17_18_mid	203..253	CDD:463454	16/69 (23%)