DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SoxN and Hmgxb4

DIOPT Version :9

Sequence 1:	NP_001260269.1	Gene:	SoxN / 44275	FlyBaseID:	FBgn0029123	Length:	761	Species:	Drosophila melanogaster
Sequence 2:	NP_001100882.1	Gene:	Hmgxb4 / 307667	RGDID:	1305783	Length:	598	Species:	Rattus norvegicus

Alignment Length:	284	Identity:	54/284 - (19%)
Similarity:	101/284 - (35%)	Gaps:	68/284 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 QSHLTHSQLSHHNHHHHHMS-----AHIAASQSPNP-------------LSSLQSSMANTLNGSQ 91
            ||.|..::..|.:....|.|     .....||.|.|             |...:||.|..|...:
  Rat   242 QSLLKTARKKHKSSSDSHSSPGPEGCGSDGSQLPEPHSANLDITGLDPILVESESSSAGELEAGE 306

  Fly    92 V-----------GQQQQQQQQQQSSPLHSSSELSPTQSSIGSHHMTSPVSHQQHTQQQQHGQQQH 145
            :           .::.::.::::....|.....|.|:.|....|.|:               ::|
  Rat   307 LVIDDSYREIKKKKKSKKSKKKKDKDRHKEKRHSRTKRSSTREHGTA---------------REH 356

  Fly   146 LGAGSALSSL---------TGGSSNNNNNSATANKNQQHADRVKRP-MNAFMVWSRGQRRKMASD 200
            :...|..||:         |.|...........::.::..::.|:. |:|:.|:.:..|..:.:|
  Rat   357 MLVSSPASSIPTLPLPALHTDGHGEKKKKKEEKDRERERGEKPKKKNMSAYQVFCKEYRVTIVAD 421

  Fly   201 NPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKTKEKYP 265
            :|.:...|:||:|...||.|.|.:|            :..|:...|....:.|.:..|..::...
  Rat   422 HPGIDFGELSKKLAEVWKQLPEKDK------------LIWKQKAQYLQHKQNKAEATTVKRKASS 474

  Fly   266 MGGLMP--GQTVGGGAPGEPVTPT 287
            ..|.|.  ..:||..:|.:...||
  Rat   475 AEGTMKVRASSVGILSPQKKSPPT 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	18/71 (25%)
Hmgxb4	NP_001100882.1	DUF4171	107..225	CDD:290491
Hmgxb4	NP_001100882.1	HMG-box	400..463	CDD:238037	18/74 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1641977at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010