DRSC/TRiP Functional Genomics Resources

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Protein Alignment SoxN and Sox8

DIOPT Version :10

Sequence 1:NP_001260269.1 Gene:SoxN / 44275 FlyBaseID:FBgn0029123 Length:761 Species:Drosophila melanogaster
Sequence 2:NP_001100459.1 Gene:Sox8 / 302993 RGDID:1309072 Length:463 Species:Rattus norvegicus


Alignment Length:487 Identity:121/487 - (24%)
Similarity:168/487 - (34%) Gaps:175/487 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   179 VKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEH 243
            |||||||||||::..|||:|...|.:||:|:||.||..|:.|||||||||::||:|||..|.|:|
  Rat    99 VKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDH 163

  Fly   244 PDYKYRPRRKTKTLTKTKEK--------YPMGGLMPGQTVGG-------------GAPGEPVTPT 287
            |||||:|||:....|...:.        :|.|.:....||.|             |.|..|.|| 
  Rat   164 PDYKYQPRRRKSVKTGRSDSDSGTELGHHPGGPMYKTDTVLGDAHRHSDHTGQTHGPPTPPTTP- 227

  Fly   288 RVQGQPGQNQSLNGSGGSAAAAAAAAAAAAQQ-----------------ARQDMYQMNAPNGYMP 335
                :...:|:.|||.............:.:|                 :..|.:.::..:.|:|
  Rat   228 ----KTDLHQASNGSKQELRLEGRRLVDSGRQNIDFSNVDISELSSEVISNMDTFDVHEFDQYLP 288

  Fly   336 -NGYMMHADPAGAAAYQTSYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPS 399
             ||:...|.....|....||.|..|:                :...:|...||..:   ..|:||
  Rat   289 LNGHSALATEPSQATASGSYGGASYS----------------HSGATGIGASPVWA---HKGAPS 334

  Fly   400 PYGGSSLQQQPGSPTPYGGGGGGGGQVSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIM 464
                     ...|||..|               |....||:|.:|||       :.|:.::....
  Rat   335 ---------ASASPTEAG---------------PLRPHIKTEQLSPS-------HYNDQSHGSPG 368

  Fly   465 KREYSSAAAAAAAAAAAAAAGGGELNHLMNMYHLPDEQRHLLHYQTDSPDLQQQHQSMQQQQQHL 529
            :.:|.|.:|.|:...||:|.....                ....|.|..|||             
  Rat   369 RADYGSYSAQASVTTAASATAASS----------------FASAQCDYTDLQ------------- 404

  Fly   530 PQQHLSQQHQQIPQQHHTMQQQQQQHHLQHQQSLRAMAPLAHMXEMASAYGAAGSSVSVSPPLPP 594
                                                          ||.|      .|..|..||
  Rat   405 ----------------------------------------------ASNY------YSPYPGYPP 417

  Fly   595 YMPTAPQQQQQQQQQQQQLLNGRPSPTASGSS 626
            .:...|.....::.....||||...|.|...|
  Rat   418 SLYQYPYFHSSRRPYASSLLNGLSMPPAHSPS 449

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SoxNNP_001260269.1 HMG-box_SoxB 177..252 CDD:438790 47/72 (65%)
Sox8NP_001100459.1 Sox_N 18..86 CDD:463586
HMG-box_SoxE 98..172 CDD:438840 47/72 (65%)
Blue background indicates that the domain is not in the aligned region.

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