DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SoxN and HBP1

DIOPT Version :9

Sequence 1:	NP_001260269.1	Gene:	SoxN / 44275	FlyBaseID:	FBgn0029123	Length:	761	Species:	Drosophila melanogaster
Sequence 2:	NP_001231191.1	Gene:	HBP1 / 26959	HGNCID:	23200	Length:	524	Species:	Homo sapiens

Alignment Length:	153	Identity:	45/153 - (29%)
Similarity:	70/153 - (45%)	Gaps:	13/153 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 SSELSPTQSSIGSHHMTSPVSHQQHTQQQQHGQQQHLGAGSALSSLTG--GSSNNNNNSATANKN 172
            |.:.:|..||  :.::.|.::.|:.......|......|.|..|...|  |||..::||..|...
Human   366 SYDFTPMDSS--AVYVLSSMARQRRASLSCGGPGGQDFARSGFSKNCGSPGSSQLSSNSLYAKAV 428

  Fly   173 QQHA---------DRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPF 228
            :.|:         ::.||||||||::::..|.:.....|...|..||..||.:||.:...|:|.:
Human   429 KNHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMY 493

  Fly   229 IDEAKRLRAVHMKEHPDYKYRPR 251
            ..|||.|.....:.:||...|.|
Human   494 TLEAKALAEEQKRLNPDCWKRKR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	25/70 (36%)
HBP1	NP_001231191.1	AXH	224..350	CDD:197779
HBP1	NP_001231191.1	SOX-TCF_HMG-box	443..514	CDD:238684	25/70 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1641977at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920