| Sequence 1: | NP_001260269.1 | Gene: | SoxN / 44275 | FlyBaseID: | FBgn0029123 | Length: | 761 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_035694.1 | Gene: | Sry / 21674 | MGIID: | 98660 | Length: | 395 | Species: | Mus musculus |
| Alignment Length: | 593 | Identity: | 151/593 - (25%) |
|---|---|---|---|
| Similarity: | 196/593 - (33%) | Gaps: | 266/593 - (44%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 179 VKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEH 243
Fly 244 PDYKYRPRRKTKTLTKTKEKYPMGGLMPGQTVGGGAPGEPVTPTRVQG--QPGQNQSLNGSGGSA 306
Fly 307 AAAAAAAAAAAQQARQD------MYQMNAPNGY-----MPNGYMMHADPAGAAAYQTSYMGQHYA 360
Fly 361 AQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPSPYGGSSLQQQPGSPTPYGGGGGGGGQ 425
Fly 426 VSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAAAAAAAAAGGGELN 490
Fly 491 HLMNMYHLPDEQRHLLHYQTDSPDLQQQHQSMQQQQQHLPQQHLSQQHQQIPQ--QHHTMQQQQQ 553
Fly 554 QH-HLQHQQSLRAMAPLAHMXEMASAYGAAGSSVSVSPPLPPYMPTAPQQQQQ---QQQQQQQLL 614
Fly 615 NGRPSPTASGSSGGRSSAHSSGHTAAHSPALAAAYQLTPSAATSSATSAAAAAATAAAVAAAAAA 679
Fly 680 GSSFAASASMLDMQQQHLEEQQQHH------HLHYQQQQQ--QHYQQQQQ-----QQQQLQHLPQ 731
Fly 732 QQQHQLYH 739 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SoxN | NP_001260269.1 | SOX-TCF_HMG-box | 178..249 | CDD:238684 | 44/69 (64%) |
| Sry | NP_035694.1 | Sufficient for interaction with KPNB1. /evidence=ECO:0000250|UniProtKB:Q05066 | 4..81 | 47/75 (63%) | |
| SOX-TCF_HMG-box | 4..74 | CDD:238684 | 43/68 (63%) | ||
| Required for nuclear localization. /evidence=ECO:0000250|UniProtKB:Q05066 | 6..22 | 14/15 (93%) | |||
| Sufficient for interaction with EP300. /evidence=ECO:0000250|UniProtKB:Q05066 | 52..84 | 15/31 (48%) | |||
| Required for nuclear localization. /evidence=ECO:0000250|UniProtKB:Q05066 | 75..81 | 2/5 (40%) | |||
| Necessary for interaction with ZNF208 isoform KRAB-O. /evidence=ECO:0000269|PubMed:15469996 | 92..144 | 14/83 (17%) | |||
| Necessary for interaction with SLC9A3R2 and nuclear accumulation of SLC9A3R2. /evidence=ECO:0000269|PubMed:16166090 | 94..138 | 10/61 (16%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 142..361 | 85/414 (21%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0527 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000028 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR10270 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.910 | |||||