Protein Alignment SoxN and Sox7

DIOPT Version :9

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_035576.1
• Gene: Sox7 / 20680
• MGIID: 98369
• Length: 380
• Species: Mus musculus
• Alignment Length: 510
• Identity: 116/510 - (22%)
• Similarity: 172/510 - (33%)
• Gaps: 199/510 - (39%)

  Fly   178 RVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKE 242
            |::|||||||||::.:|:::|..||.:||:|:||.||..||.|:.|:|||::|||:|||..||::
Mouse    44 RIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQD 108

  Fly   243 HPDYKYRPRRKT--KTLTKTKEKYPMGGLMPGQTVGGGAPGEPVTPTRVQGQPGQNQSLNGSGGS 305
            :|:||||||||.  |.|.|..:        ||..:...:..:...|.:           ||.|
Mouse   109 YPNYKYRPRRKKQGKRLCKRVD--------PGFLLSSLSRDQNTLPEK-----------NGIG-- 152

  Fly   306 AAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAGAAAYQTSYMGQHYAAQRYDMGHMY 370
                        :..::|..:. :|...:|..:..:.:  ||||...|.
Mouse   153 ------------RGEKEDRGEY-SPGATLPGLHSCYRE--GAAAAPGSV---------------- 186

  Fly   371 NNGYAMYQTVSGGQTSPYGSSLQQPGSPSP---------YGGSSLQQQPGSPTPYGGGGGGGGQV 426
                         .|.|||  |..|...||         :..||.|::.|.|
Mouse   187 -------------DTYPYG--LPTPPEMSPLDALEPEQTFFSSSCQEEHGHP------------- 223

  Fly   427 SCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAAAAAAAAAGGGELNH 491
               .|.|   .:...|.||                     |::.:....:....:.|.|
Mouse   224 ---HHLP---HLPGPPYSP---------------------EFTPSPLHCSHPLGSLALG------ 255

  Fly   492 LMNMYHLPDEQRHLLHYQTDSPDLQQQHQSMQQQQQHLPQQHLSQQHQQIPQQHHTMQQQQQQHH 556
                               .||.:     ||.......|.......|......|..:|
Mouse   256 -------------------QSPGV-----SMMSSVSGCPPSPAYYSHATYHPLHPNLQ------- 289

  Fly   557 LQHQQSLRAMAPLAHMXEMASAYGAAGSSVSVSPPLPPYMPTAPQQQQ------QQQQQQQQLLN 615
                         ||: :::            .||..|...|..|..|      ..:.:..|.||
Mouse   290 -------------AHLGQLS------------PPPEHPGFDTLDQLSQVELLGDMDRNEFDQYLN 329

  Fly   616 GRPSPTASGSSGGRSSAHSSGHTAAHSPALAAAYQLTPSAATSSATSAAAAAATA 670
                     :.|...||...|....|.|    ..|.||:..|.::..:..|.|||
Mouse   330 ---------TPGHPDSAAGVGTLTGHVP----LSQGTPTGPTETSLISVLADATA 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	39/70 (56%)
Sox7	NP_035576.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..43
		SOX-TCF_HMG-box	44..115	CDD:238684	39/70 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	139..167		6/53 (11%)
		Sox_C_TAD	175..378	CDD:288887	59/345 (17%)
		Required for beta-catenin-binding	323..328		1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910