Protein Alignment SoxN and Sox2

DIOPT Version :9

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_035573.3
• Gene: Sox2 / 20674
• MGIID: 98364
• Length: 319
• Species: Mus musculus
• Alignment Length: 395
• Identity: 149/395 - (37%)
• Similarity: 184/395 - (46%)
• Gaps: 110/395 - (27%)

  Fly   131 HQQHTQQQQHGQQQHLGAGSALSSLTGGSSNNNNNSATANKNQQHADRVKRPMNAFMVWSRGQRR 195
            :...|:.:..|.||..|.        ||...|...:||....:...|||||||||||||||||||
Mouse     3 NMMETELKPPGPQQASGG--------GGGGGNATAAATGGNQKNSPDRVKRPMNAFMVWSRGQRR 59

  Fly   196 KMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTKTLTKT 260
            |||.:|||||||||||||||:||.|||:||||||||||||||:|||||||||||||||||||.|
Mouse    60 KMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMK- 123

  Fly   261 KEKYPM-GGLMPGQTVGGGAPGEPVTPTRVQGQPGQNQSLNGSGGSAAAAAAAAAAAAQQARQDM 324
            |:||.: |||:                     .||.|...:|.|      ..|...|....|.|.
Mouse   124 KDKYTLPGGLL---------------------APGGNSMASGVG------VGAGLGAGVNQRMDS 161

  Fly   325 YQMNAPNGYMPNGYMMHADPAGAAAYQTSYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQT---- 385
            |.  ..||:....|.|..:..|..  |...:..|.|||...| |.|:.....|.:::..||
Mouse   162 YA--HMNGWSNGSYSMMQEQLGYP--QHPGLNAHGAAQMQPM-HRYDVSALQYNSMTSSQTYMNG 221

  Fly   386 SP-YGSSLQQPGSPSPYGGSSLQQQPGSPTPYGGGGGGGGQVSCQSHSPSDSSIKSEPVSPSPSA 449
            || |..|..|.|:|    |.:|              |..|.|           :||| .|.||..
Mouse   222 SPTYSMSYSQQGTP----GMAL--------------GSMGSV-----------VKSE-ASSSPPV 256

  Fly   450 IALNNNNNINNNHIMKREYSSAAAAAAAAAAAAAAGGGELNHLMNMY----HLPD----EQRHLL 506
            :.                 ||:.:.|...|       |:|..:::||    .:|:    .:.|:.
Mouse   257 VT-----------------SSSHSRAPCQA-------GDLRDMISMYLPGAEVPEPAAPSRLHMA 297

  Fly   507 -HYQT 510
             |||:
Mouse   298 QHYQS 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	64/70 (91%)
Sox2	NP_035573.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		11/47 (23%)
		SOX-TCF_HMG-box	42..113	CDD:238684	64/70 (91%)
		SOXp	112..202	CDD:403523	39/122 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	247..267		9/37 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..319		3/4 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_106862
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5512
SonicParanoid	1	1.000	-	-		X927
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.840