Protein Alignment SoxN and Sox17

DIOPT Version :9

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_001276393.1
• Gene: Sox17 / 20671
• MGIID: 107543
• Length: 419
• Species: Mus musculus
• Alignment Length: 500
• Identity: 136/500 - (27%)
• Similarity: 198/500 - (39%)
• Gaps: 141/500 - (28%)

  Fly   125 MTSP-VSHQQHTQQQQHGQQQHLGAG-------SALSSL-----------TGGSSNNNNNSATAN 170
            |:|| ..:....|.|....|..:.||       .:||.|           :.|:....:..|.|.
Mouse     1 MSSPDAGYASDDQSQPRSAQPAVMAGLGPCPWAESLSPLGDVKVKGEVVASSGAPAGTSGRAKAE 65

  Fly   171 KNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRL 235
                  .|::|||||||||::.:|:::|..||.:||:|:||.||..||.|:.:|||||::||:||
Mouse    66 ------SRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERL 124

  Fly   236 RAVHMKEHPDYKYRPRRKTKTLTKTKEKYPMGGLMPGQTVGGGAPGEPVTPTRVQGQPGQNQSLN 300
            |..||::||:|||||||: |.:.:.|.            |.||.....|.|        |..:|.
Mouse   125 RVQHMQDHPNYKYRPRRR-KQVKRMKR------------VEGGFLHALVEP--------QAGALG 168

  Fly   301 GSGGSAAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAGAAAYQTSYMGQHYAAQRYD 365
            ..||..|                |..:..|  :...||     ||| ....:.:||.|
Mouse   169 PEGGRVA----------------MDGLGLP--FPEPGY-----PAG-PPLMSPHMGPH------- 202

  Fly   366 MGHMYNNGYAMYQTVSG-GQTSPYGSSLQQPGSPSPYGGSSLQQQP---GSPTPYGGGGGGGGQV 426
                       |:...| |..:..|..|..|.: ||..|  ::|.|   .:|.|     |.....
Mouse   203 -----------YRDCQGLGAPALDGYPLPTPDT-SPLDG--VEQDPAFFAAPLP-----GDCPAA 248

  Fly   427 SCQSHSP-SDSSIKSEP------VSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAAAAAAAAA 484
            ...:::| ||.::..||      |.|.||..|:..        |:....:......|..:.||:|
Mouse   249 GTYTYAPVSDYAVSVEPPAGPMRVGPDPSGPAMPG--------ILAPPSALHLYYGAMGSPAASA 305

  Fly   485 GGGELNHLMNMYHLPDEQRHLLHYQTDSPDLQQQHQSMQQQQQHLPQQHLSQQHQQIPQQHHTMQ 549
            |.|        :|...:|.  |..|...|..||||.:      |.|.|. |...:.:|.:..|..
Mouse   306 GRG--------FHAQPQQP--LQPQAPPPPPQQQHPA------HGPGQP-SPPPEALPCRDGTES 353

  Fly   550 QQQQQ-----HHLQHQQSLRAMAPLAHMXEMASAYGAAGSSVSVS 589
            .|..:     ...:.:|.|    |..:. ||...|......|::|
Mouse   354 NQPTELLGEVDRTEFEQYL----PFVYKPEMGLPYQGHDCGVNLS 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	40/70 (57%)
Sox17	NP_001276393.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		7/25 (28%)
		SOX-TCF_HMG-box	67..138	CDD:238684	40/70 (57%)
		Sox17_18_mid	203..253	CDD:403331	14/57 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..356		19/69 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910