DRSC/TRiP Functional Genomics Resources

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Protein Alignment SoxN and Sox15

DIOPT Version :9

Sequence 1:NP_001260269.1 Gene:SoxN / 44275 FlyBaseID:FBgn0029123 Length:761 Species:Drosophila melanogaster
Sequence 2:NP_033261.1 Gene:Sox15 / 20670 MGIID:98363 Length:231 Species:Mus musculus


Alignment Length:317 Identity:104/317 - (32%)
Similarity:127/317 - (40%) Gaps:103/317 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   109 SSSELSPTQSSIGSHHMTSPVSHQQHTQQQQHGQQQHLGAGSALSSLTGGSSNNNNNSATANKNQ 173
            :||..:.|.|   .|...|..|.....|:|:.|.......|..|                     
Mouse     4 TSSSQAETWS---LHPRASTASLPLGPQEQEAGGSPGASGGLPL--------------------- 44

  Fly   174 QHADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAV 238
               ::||||||||||||..|||:||..||||||||||||||||||.|.:.|||||::|||||||.
Mouse    45 ---EKVKRPMNAFMVWSSVQRRQMAQQNPKMHNSEISKRLGAQWKLLGDEEKRPFVEEAKRLRAR 106

  Fly   239 HMKEHPDYKYRPRRKTKTLTKTKEKYPMGGLMPGQTVGGG--------APGEPVTPTRVQGQPGQ 295
            |::::||||||||||:|..:.        |.:|....|||        .||...|          
Mouse   107 HLRDYPDYKYRPRRKSKNSST--------GSVPFSQEGGGLACGGSHWGPGYTTT---------- 153

  Fly   296 NQSLNGSGGSAAAAAAAAAAAAQQARQDMYQ-MNAPNGYMPNGY-MMHADPAGAAAYQTSYMGQH 358
             |...|.|                     || .|....|:|..| ..|..|  .|....::....
Mouse   154 -QGSRGFG---------------------YQPPNYSTAYLPGSYTSSHCRP--EAPLPCTFPQSD 194

  Fly   359 YAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPSPYGGSSLQQQPGSPTP 415
            ...|                    |:..|..|....|.|.:||..|    ..|:|.|
Mouse   195 PRLQ--------------------GELRPSFSPYLSPDSSTPYNTS----LAGAPMP 227

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SoxNNP_001260269.1 SOX-TCF_HMG-box 178..249 CDD:238684 53/70 (76%)
Sox15NP_033261.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..45 12/67 (18%)
Required to promote HAND1 transcriptional activator activity. /evidence=ECO:0000269|PubMed:16759287 1..45 12/67 (18%)
SOX-TCF_HMG-box 46..117 CDD:238684 53/70 (76%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 111..136 13/32 (41%)
Interaction with FHL3. /evidence=ECO:0000269|PubMed:17363903 136..181 16/76 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 186..231 12/66 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0527
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000028
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10270
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.910

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