DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment SoxN and Sox11

DIOPT Version :9

Sequence 1:NP_001260269.1 Gene:SoxN / 44275 FlyBaseID:FBgn0029123 Length:761 Species:Drosophila melanogaster
Sequence 2:NP_033260.4 Gene:Sox11 / 20666 MGIID:98359 Length:395 Species:Mus musculus


Alignment Length:334 Identity:100/334 - (29%)
Similarity:138/334 - (41%) Gaps:66/334 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   179 VKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEH 243
            :|||||||||||:.:|||:...:|.|||:|||||||.:||.|.:|||.|||.||:|||..||.::
Mouse    49 IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADY 113

  Fly   244 PDYKYRPRRKTKTLTKTKEKYPMGGLMPGQTVGGG----APGEPVTPTRVQGQPGQNQSLNGSGG 304
            ||||||||:|.||....|   |..|..|.::..|.    .||:.....:...         |..|
Mouse   114 PDYKYRPRKKPKTDPAAK---PSAGQSPDKSAAGAKAAKGPGKKCAKLKAPA---------GKAG 166

  Fly   305 SAAAAAAAAAAAAQQAR-------------QDMYQMNAPNGYMPNGYMMHADPAGA------AAY 350
            :..||.....||.:.|:             .|..|:..    .|:......:||.:      ...
Mouse   167 AGKAAQPGDCAAGKAAKCVFLDDDDEDDDEDDELQLRP----KPDADDDDDEPAHSHLLPPPTQQ 227

  Fly   351 QTSYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQ---QPGSPSPYGGSSLQQQPGS 412
            |...:.:.|:..:....          .|:|....||.|:||.   :.|....|...::.:|...
Mouse   228 QPPQLLRRYSVAKVPAS----------PTLSSAAESPEGASLYDEVRAGGRLYYSFKNITKQQPP 282

  Fly   413 PTPYGGGGGGGGQVSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAA 477
            |.|..........||..|.|.|.|...:|........::||              :|..|.:|..
Mouse   283 PAPPALSPASSRCVSTSSSSGSSSGSGAEDADDLMFDLSLN--------------FSQGAHSACE 333

  Fly   478 AAAAAAAGG 486
            ....|.|.|
Mouse   334 QPLGAGAAG 342

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SoxNNP_001260269.1 SOX-TCF_HMG-box 178..249 CDD:238684 45/69 (65%)
Sox11NP_033260.4 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
SOX-TCF_HMG-box 48..119 CDD:238684 45/69 (65%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 114..258 37/169 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 276..312 9/35 (26%)
Required for transcriptional activation activity and synergistic coactivation of transcriptional activity with POU3F2. /evidence=ECO:0000269|PubMed:18403418 363..395
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0527
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000028
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10270
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.910

Return to query results.
Submit another query.