DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SoxN and hmg-3

DIOPT Version :9

Sequence 1:	NP_001260269.1	Gene:	SoxN / 44275	FlyBaseID:	FBgn0029123	Length:	761	Species:	Drosophila melanogaster
Sequence 2:	NP_491688.1	Gene:	hmg-3 / 172250	WormBaseID:	WBGene00001973	Length:	689	Species:	Caenorhabditis elegans

Alignment Length:	254	Identity:	46/254 - (18%)
Similarity:	90/254 - (35%)	Gaps:	72/254 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 SAHIAASQSPNPL------------SSL---------QSSMANTLNGSQVGQQQQQQQQQQSSPL 107
            |.|.|.|.|....            |||         .:.:.:.||..::..:...:...:|:..
Worm   376 SCHFARSDSGTVTRTFDFEIDLKTGSSLTFSAMDKEENNKLFDYLNKKEIKIRNSHRIDNKSAGY 440

  Fly   108 HSSSE--LSPTQSSIGS-----------------HHMTSPVSHQQHTQQQQHGQ----QQHLGAG 149
            .||.|  :.|.:|::.:                 :.:...:..|::.:....|.    .....:|
Worm   441 GSSDEDDIDPYKSTVKAEGREQDDDSDDESTDEDYDLDKDMKKQKNDKDSSEGSGSEPDDEYDSG 505

  Fly   150 SAL-SSLTGGSSNNNNN-------------------------SATANKNQQHADRVKRPMNAFMV 188
            |.. :|.||.|..:..|                         :....|..:..:..||...|:::
Worm   506 SEKDASGTGESDPDEENIEPKKKESKEKKNKREKKEKPVKEKAVKKGKKTKDPNEPKRATTAYII 570

  Fly   189 WSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYK 247
            |....|..|..|...:  .:::|:.||:||.:|..:|:.:.|:|.:.:|.:..|..:||
Worm   571 WFNANRNSMKEDGDTL--GDVAKKAGAKWKSMSADDKKEWNDKAAQDKARYEAEMKEYK 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	20/70 (29%)
hmg-3	NP_491688.1	POB3	20..497	CDD:227494	18/120 (15%)
		SSrecog	75..285	CDD:281523
		PH2_SSRP1-like	332..429	CDD:270051	10/52 (19%)
		HMGB-UBF_HMG-box	561..624	CDD:238686	18/64 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910