Protein Alignment SoxN and sox10

DIOPT Version :10

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: NP_571950.1
• Gene: sox10 / 140616
• ZFINID: ZDB-GENE-011207-1
• Length: 485
• Species: Danio rerio
• Alignment Length: 520
• Identity: 131/520 - (25%)
• Similarity: 202/520 - (38%)
• Gaps: 142/520 - (27%)

  Fly   104 SSPLHSSSELSPTQSSIGSHHMTSPVSHQQHTQQQQH-------------GQQQHL-GAGSALSS 154
            |:..||.||:          .|:..||...|:....|             |||..: |.|...:.
Zfish     2 SAEEHSMSEV----------EMSPGVSDDGHSMSPGHSSGAPGGADSPLPGQQSQMSGIGDDGAG 56

  Fly   155 LTGGSSNNNNNS---------------------------ATANKNQQHADRVKRPMNAFMVWSRG 192
            ::||.|..::..                           ...|...:....|||||||||||::.
Zfish    57 VSGGVSVKSDEEDDRFPIGIREAVSQVLNGYDWTLVPMPVRVNSGSKSKPHVKRPMNAFMVWAQA 121

  Fly   193 QRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKTK-- 255
            .|||:|...|.:||:|:||.||..|:.|:|::|||||:||:|||..|.|::|:|||:|||:..
Zfish   122 ARRKLADQYPHLHNAELSKTLGKLWRLLNETDKRPFIEEAERLRKQHKKDYPEYKYQPRRRKNGK 186

  Fly   256 -------------TLTKTKEKYPM-------GGLMPGQTVGGG-----------APGEPVTP-TR 288
                         .::.::..|..       || ..|..:|.|           .|..|.|| |.
Zfish   187 PGSSSEADAHSEGEVSHSQSHYKSLHLEVAHGG-AAGSPLGDGHHPHATGQSHSPPTPPTTPKTE 250

  Fly   289 VQ-GQPGQNQSLNGSG----GSAAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAGAA 348
            :| |:.|:.:...|:.    |..|..::|:::|:.:...|.  .|...|.:.:..|.:.:|
Zfish   251 LQGGKSGEGKREGGASRSGLGVGADGSSASSSASGKPHIDF--GNVDIGEISHDVMANMEP---- 309

  Fly   349 AYQTSYMGQHYAAQRYDMGHMYNNGYAMYQ-TVSGGQTSP---YG-SSLQQPGSPSPYGGSSLQQ 408
                      :....:|. ::..||:.... |.|.|..:|   || ||.....|.......|.||
Zfish   310 ----------FDVNEFDQ-YLPPNGHPQASATASAGSAAPSYTYGISSALAAASGHSTAWLSKQQ 363

  Fly   409 QPGSPTPYGGGGGGGGQVSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAA 473
            .|..  .:.|..||..|:..::|.|.|::.....|:.:|..:.               .||||..
Zfish   364 LPSQ--QHLGADGGKTQIKSETHFPGDTAASGSHVTYTPLTLP---------------HYSSAFP 411

  Fly   474 AAAAAA-----AAAAAGGGELNH---LMNMY----HLPDEQRHLLHYQTDSPDLQQQHQSMQQQQ 526
            :.|:.|     |...|.|....|   ...:|    ::...||.|.....|...:.|.|.....:|
Zfish   412 SLASRAQFAEYAEHQASGSYYAHSSQTSGLYSAFSYMGPSQRPLYTAIPDPGSVPQSHSPTHWEQ 476

  Fly   527  526
            Zfish   477  476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	HMG-box_SoxB	177..252	CDD:438790	43/74 (58%)
sox10	NP_571950.1	Sox_N	13..97	CDD:463586	13/83 (16%)
		HMG-box_SoxE	107..181	CDD:438840	43/73 (59%)