DRSC/TRiP Functional Genomics Resources

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Protein Alignment SoxN and SOX21

DIOPT Version :9

Sequence 1:NP_001260269.1 Gene:SoxN / 44275 FlyBaseID:FBgn0029123 Length:761 Species:Drosophila melanogaster
Sequence 2:NP_009015.1 Gene:SOX21 / 11166 HGNCID:11197 Length:276 Species:Homo sapiens


Alignment Length:328 Identity:131/328 - (39%)
Similarity:147/328 - (44%) Gaps:120/328 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   177 DRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMK 241
            |.|||||||||||||.||||||.:|||||||||||||||:||.|:||||||||||||||||:|||
Human     6 DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMK 70

  Fly   242 EHPDYKYRPRRKTKTLTKTKEK------YPMGGLM----PGQTVGGG---APGEPVTPTRVQGQP 293
            ||||||||||||.|||.| |:|      |.:||:.    |....|.|   ..|..:.|       
Human    71 EHPDYKYRPRRKPKTLLK-KDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLVP------- 127

  Fly   294 GQNQSLNGSGGSAAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAGAAAYQTSYMGQH 358
               :||..:...||||||||||..               :.|......|..|.|||..:.|    
Human   128 ---ESLLANPEKAAAAAAAAAARV---------------FFPQSAAAAAAAAAAAAAGSPY---- 170

  Fly   359 YAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPSPYGGSSLQQQPGSPTPYGGGGGGG 423
                     .:.:.|..|.:..|.....||.|||                  |.||  .|.|...
Human   171 ---------SLLDLGSKMAEISSSSSGLPYASSL------------------GYPT--AGAGAFH 206

  Fly   424 GQVSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAAAAAAAAAGGGE 488
            |                                                ||||||||||||||..
Human   207 G------------------------------------------------AAAAAAAAAAAAGGHT 223

  Fly   489 LNH 491
            .:|
Human   224 HSH 226

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SoxNNP_001260269.1 SOX-TCF_HMG-box 178..249 CDD:238684 62/70 (89%)
SOX21NP_009015.1 SOX-TCF_HMG-box 7..78 CDD:238684 62/70 (89%)
SOXp 77..>95 CDD:403523 12/18 (67%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0527
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000028
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10270
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.910

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