Protein Alignment SoxN and sox21

DIOPT Version :10

• Sequence 1: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Sequence 2: XP_002939326.1
• Gene: sox21 / 100038091
• XenbaseID: XB-GENE-486445
• Length: 271
• Species: Xenopus tropicalis
• Alignment Length: 317
• Identity: 126/317 - (39%)
• Similarity: 144/317 - (45%)
• Gaps: 113/317 - (35%)

  Fly   177 DRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMK 241
            |.|||||||||||||.||||||.:|||||||||||||||:||.|:|:||||||||||||||:|||
 Frog     6 DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTEAEKRPFIDEAKRLRAMHMK 70

  Fly   242 EHPDYKYRPRRKTKTLTKTKEKY----PMG--GLMPGQTVGGGAPGEPVTPTRVQGQPGQNQSLN 300
            ||||||||||||.|||.| |:|:    |.|  |...|..|.|           :.|......||.
 Frog    71 EHPDYKYRPRRKPKTLLK-KDKFAFPMPYGFTGDHDGLKVAG-----------LHGAGALTDSLL 123

  Fly   301 GSGGSAAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAGAAAYQTSYMGQHYAAQRYD 365
            .:...||||||||||..               :.|......|..|.|||     .|.::....:|
 Frog   124 SNPEKAAAAAAAAAARV---------------FFPPSAAAAAAAAAAAA-----GGANHPYSLFD 168

  Fly   366 MGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPSPYGGSSLQQQPGSPTPYGGGGGGGGQVSCQS 430
            :..      .|.:..|...:.||.||:   |.|...||:.    ||
 Frog   169 LSS------KMAEITSSSSSLPYTSSI---GYPQASGGAF----PG------------------- 201

  Fly   431 HSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAAAAAAAAAGGG 487
                                                       .|||||||||||||
 Frog   202 -------------------------------------------VAAAAAAAAAAGGG 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SoxN	NP_001260269.1	HMG-box_SoxB	177..252	CDD:438790	65/74 (88%)
sox21	XP_002939326.1	HMG-box_SoxB	6..85	CDD:438790	68/78 (87%)
		SOXp	77..>95	CDD:463537	12/18 (67%)