Protein Alignment disp and Ptr

DIOPT Version :9

• Sequence 1: NP_524734.2
• Gene: disp / 44274
• FlyBaseID: FBgn0029088
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: NP_001246145.1
• Gene: Ptr / 35546
• FlyBaseID: FBgn0262867
• Length: 1169
• Species: Drosophila melanogaster
• Alignment Length: 940
• Identity: 178/940 - (18%)
• Similarity: 307/940 - (32%)
• Gaps: 323/940 - (34%)

  Fly   349 KMDNHCNEIPHCRAPEECKRLNIVFNVLNFLTDFSFIKSNDSNVYLKYAMIFIPVAQSNRLLPLF 413
            :.:|.|.|             |.:.|:...:.|   |::...|  |.:..:|.||.....|.|:|
  Fly   145 RWENECFE-------------NDILNLDALMDD---IEAGQLN--LTFPFMFNPVTWDAHLFPVF 191

  Fly   414 HEWEDVELINELVEVVAMDL--------------GLENELFNELLLTDVWLVSLGGTF------- 457
            .....:...|.::.|.|:.|              |.|   :.|..|..|......|.|
  Fly   192 FGGTKLTEDNYVISVPAIQLVYFVTADTKRQDAKGAE---WEETFLRVVGNAENSGQFKHISVSY 253

  Fly   458 -------------------VMASVWLYTG---------------SAFITLMSCVAICFSLGLAYF 488
                               ..:|.:|..|               ..|:.||..|:...:. ||.|
  Fly   254 FASRTLDHELEKNTKTVVPYFSSTFLLMGLFSIITCMMGDAVRSKPFLGLMGNVSAIMAT-LAAF 317

  Fly   489 FYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTERFSNRCTLTTQSQSALPTLENS 553
            ..|:....||.. :||.|..::||||.||.|:.|..|.               ::::.:|..|.
  Fly   318 GLAMYCGIEFIG-INLAAPFLMIGIGIDDTFVMLAGWR---------------RTKAKMPVAER- 365

  Fly   554 DHTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWL 618
                     |.|.|..||.|:.:||:|...:|.....|...:::.|..::...|...:|..||:.
  Fly   366 ---------MGLMMSEAAVSITITSVTDFISFLIGIISPFRSVRIFCTYSVFAVCFTFLWHITFF 421

  Fly   619 PASVSI--------MERLFATRMSCHHPMSIKLIHACKKSINRFCQMFEECITKSIMNYAYLWLL 675
            .|.::|        :..:|..|:   .|||:.:                    |...|:.|. .:
  Fly   422 AACMAISGYRERKNLHSIFGCRV---QPMSVAI--------------------KEKRNFLYK-AI 462

  Fly   676 IFGALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEVYSSLKQQFWFEKPLQAYENFKMHMHFV 740
            :.|.:.|:.       |...:..|.|..:                .:|:..:.|..|.|
  Fly   463 MAGGIDAND-------PDNPIDNKDHMLM----------------AFFKDKMAAVINNK------ 498

  Fly   741 WGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKETLGMLLPNCF-IE 804
                                               |    |:::....|....:|.    |: |.
  Fly   499 -----------------------------------W----CKAIIILAFASYLVGA----CYGIT 520

  Fly   805 NLIDYMKRRCIDDMDSTRK---DRSPCCDAQFPFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKF 866
            .:.:.::||.:...||...   ||......:||:...:.                    :|||..
  Fly   521 QIKEGLERRKLSREDSYSVEFFDREDDYYREFPYRMQVI--------------------IAGPLN 565

  Fly   867 AEAPRLETEDYLGMSGNESAEYSTNGSFTPLLVKALVIEFESNVAYSTIYANIRQ-FYESV-EHW 929
            ...|.::.:.....|..|...|.|:..:|...:::.:...|.|.....:..:..| |.::| |||
  Fly   566 YSDPLVQEQVENLTSTLEHTSYVTSRRYTESWLRSFLSFLERNNELLNVTVDDEQTFIDAVKEHW 630

  Fly   930 FQMQLKTAPPELQGGWFTSDLKF----------------YNVQDT-------------------- 958
            .          ..|..|:.|::|                .|:.||
  Fly   631 L----------FPGNPFSLDVRFNEDETQIIASRFLIQAVNITDTNHEKEMVRDLRQICKDSPLN 685

  Fly   959 --LSHDTFV--------------AICLAMAASLAVLLCFTVNILISI---YAVLTVSLSIFNTVA 1004
              :.|..||              |:.:.....:.:...|..|||.|:   ::|:::.|.:...:|
  Fly   686 ASIFHPYFVFFDQFELVRPVSLQAMVIGAIIMMIISFVFIPNILCSLWVAFSVISIELGVAGYMA 750

  Fly  1005 VLILLGWQLNILESIAVST---AIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAA 1066
            :     |.:| |:||::..   .||.:|||:.|....|..|..:...|..:..|..:..|.:..:
  Fly   751 L-----WDVN-LDSISMINLIMCIGFSVDFTAHICYTYMSSKKRSPKARVREALHSLGLPIIQGS 809

  Fly  1067 TTTGLAGGIMMASNILPYIQIGVFLVVVMIVSWF---YATFFLMSLLRVAGPQHGFLELKWPLWS 1128
            ::|.|  ||:.......||.: ||..:|.:|.:|   :..|.|..||.:.||....      .|:
  Fly   810 SSTIL--GIVALLLAQSYIFL-VFFKMVFLVIFFGAMHGLFLLPVLLSLFGPGSCL------TWT 865

  Fly  1129 KRSSGSSKFYERKPSQVIASEQLLTPTSSA 1158
            .:..||    :.:....:...||..|.|.:
  Fly   866 GKDDGS----DAEVDDGLDDRQLEKPFSQS 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
disp	NP_524734.2	Patched	<444..1111	CDD:280598	146/782 (19%)
		MMPL	457..627	CDD:304422	46/218 (21%)
		TM_PBP1_branched-chain-AA_like	964..>1109	CDD:294309	40/167 (24%)
Ptr	NP_001246145.1	Patched	53..845	CDD:280598	165/882 (19%)
		Sterol-sensing	295..442	CDD:289145	43/173 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460575
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840