Protein Alignment disp and Disp2

DIOPT Version :10

• Sequence 1: NP_524734.2
• Gene: disp / 44274
• FlyBaseID: FBgn0029088
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: NP_001101229.2
• Gene: Disp2 / 311324
• RGDID: 1309569
• Length: 1346
• Species: Rattus norvegicus
• Alignment Length: 1203
• Identity: 317/1203 - (26%)
• Similarity: 526/1203 - (43%)
• Gaps: 245/1203 - (20%)

  Fly    12 YYHVLARRPYLVVVSIAVYCVACIIVALVLNKLPDFSDPTLGFETRGTKIGERLTAWYNLLQETD 76
            |.|::|..|..|::....:...|.:..|:.:...|||:|.||||.|.|:|..:|..|
  Rat   116 YSHMIAEWPMAVLLGCLAFIFLCTLAGLLGSPPLDFSEPLLGFEPRDTEINRKLEVW-------- 172

  Fly    77 HHGALFSNPSDLWERRRVEQGYVETKLHPNHRRRKNKHKNRNKNKRRKEQNQSSHEHHDVAQKMM 141
                                                                          |.|
  Rat   173 --------------------------------------------------------------KAM 175

  Fly   142 QFKKRLKATSSPSPNLGFDTWIGDSGVFRDYEITNDSASSSLEPTRRTEQIEYGHNTTSVDEEEH 206
            |.....|...|.||               |.|:.:.:..|:|.|.      .:|....||
  Rat   176 QALTGPKNLFSLSP---------------DPEVNSSTLLSTLSPA------AWGRAEESV----- 214

  Fly   207 QQRVQTKKSTWRLLKQAATLPTDGWADMHRRQPIEGFFCDSSPRKEYSHFV-VQRIGPNATDSLF 270
               |:||:..             |..::...   |.||| ..|.|:.:..| |...|    .||:
  Rat   215 ---VRTKRMV-------------GPVEVKEE---ENFFC-GPPEKKLAKLVFVSTSG----GSLW 255

  Fly   271 DLNGLLAMCQL-QDQITEVPSYRAFCEPEMLTTECCRPWSLPNYAAMLANKSSCFDLTTEDVTSL 334
            :|..:.:||:: |:||....|:.|.|: .....|||..|||.||.|:|:|:|||.|.|..|....
  Rat   256 NLQAIHSMCRIEQEQIRSHISFGALCQ-RSAANECCPSWSLGNYLAVLSNRSSCQDTTQADTDRT 319

  Fly   335 HTLLLGCYEYFHDLKMDNHC-----NEIPHC-RAPEECKRLNIVFNVLNFLTDFSFIKSNDSNVY 393
            ..||..|..::|...:...|     ::.|.| :.|.:|...:.|:.:|:||.|..|:....::..
  Rat   320 LALLRFCATFYHRGVLVPACVGSGQDKPPFCAQVPAKCTGSSAVYQLLHFLLDRDFLSPQTADYQ 384

  Fly   394 ---LKYAMIFIPVAQSNRLLPLFHE--WEDVELINELVEVVAMDLGLENELFNELLLTDVWLVSL 453
               ||:|::|:|:.:::.||.::.:  .:.:::.:....:..|||||:..|....|..|.....|
  Rat   385 VPSLKFALLFLPIIKTSSLLDIYLDGLGDPIKVSDNYTSISGMDLGLKPRLLKYYLAEDTMYPLL 449

  Fly   454 GGTFVMASVWLYTGSAFITLMSCVAICFSLGLAYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDV 518
            ....:...:.||..|.|||.||.:.:..||.:|:|.|.:.....:||::||.:::::.|:..:..
  Rat   450 SLVIIFFGMSLYLRSLFITFMSLLGVLGSLMVAFFLYHVAFRMAYFPFVNLASLLLLSGVCVNYT 514

  Fly   519 FLFLKIWHCVLTERFSNRCTLTTQSQSALPTLENSDHTESLENIMALTMRHAAASMFVTSLTTAG 583
            .:|..:|..               |:..:|       :..|.:.:..||.|....:.|:.|||:.
  Rat   515 LIFFDLWRL---------------SRGQVP-------SGGLAHRVGRTMHHFGYLLLVSGLTTSA 557

  Fly   584 AFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWLPASVSIMERLFA------------------ 630
            |||.||.|.:..::||.:|.||.|:.:..|.:.||||:|.:.||..|
  Rat   558 AFYGSYLSRLPTVRCFALFMGTAVLVHMGLTLLWLPATVVLHERYLAHGCVAQAQGQRGGSDPLR 622

  Fly   631 TRMSCHHPMSIKLIHACKKSINRFCQMFEECITKSIMNYAYLWLLIFGALGASSAVIVFWYPGLQ 695
            ..::.|.  .|:::......::|.  :|:..:...::.:.|:|:..|.||.|..|.|....|.|:
  Rat   623 LLLALHR--RIRILRKIFSILSRL--LFQRLLPCGVIKFRYIWICWFAALAAGGAYIGGVSPRLR 683

  Fly   696 LPEKSHF--QLFVSKHPFEVY-SSLKQQFWFEKPLQAYENFKMHMHFVWGVQAVDDGDYTNPNSY 757
            ||.....  |.|.|.||||.: :..:|||.|| .|...|...:.:..|||:..||..|..:|.:.
  Rat   684 LPILLPLGGQFFRSSHPFERFDAEYRQQFLFE-DLPPNEGGNLPVVLVWGILPVDTSDPLDPRTN 747

  Fly   758 GHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKE------TLGMLLPNCFIENLIDYMKRRCID 816
            ..:..|.:|:.||..||.|:...||..:.|.|:.:      ||      |.:|.|..:|     :
  Rat   748 SSVVSDPDFSPSSPEAQEWLQALCQGAQNQSFFGDQPEGWPTL------CLVEALQQWM-----E 801

  Fly   817 DMDSTRKDRSPCC-DAQFPFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKFAEAPRLETEDYLGM 880
            .....|.....|| .::||:.|.::.:||...                 ...::|. .|.| ||:
  Rat   802 SPSCGRLGADLCCGQSEFPWAPQLYLHCLKMM-----------------ALEQSPD-GTRD-LGL 847

  Fly   881 SGNESAEYSTNGSFTPLLVKALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGW 945
                  .:.::|:     :.|||::|::|:.|||.|..:..||..|..|...::..|||.|..||
  Rat   848 ------RFDSHGN-----LAALVLKFQTNLPYSTEYGPVHHFYTEVSRWLSTEMSKAPPGLNKGW 901

  Fly   946 FTSDLKFYNVQDTLSHDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLG 1010
            |||.|:.|::|.:||.:..|.:.||:|.:.|.||..|.|:.:|:::|..|:.::..||.:|:||.
  Rat   902 FTSTLELYSLQHSLSTEPAVVLGLALALAFATLLLGTWNVPLSLFSVAAVAGTVLLTVGLLVLLE 966

  Fly  1011 WQLNILESIAVSTAIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGI 1075
            ||||..|::.:|.::||:||.:::|.|.|.:.|..:||:...|.|.:....|.|.......:|.|
  Rat   967 WQLNTAEALFLSASVGLSVDLTVNYCISYHLCPHPDRLSRVAFSLRQTSRATAMGTGVLFASGVI 1031

  Fly  1076 MMASNILPYIQIGVFLVVVMIVSWFYATFFLMSLLRVAGPQHGFLELKWPL----WSKRSS---- 1132
            |:.|.||.|.::|:.:::|..:...:|:||..||....||:....::.||.    |...:.
  Rat  1032 MLPSTILLYRKLGIIVMMVKFLGCGFASFFFQSLCCFFGPEKNCGQILWPCAHLPWDAGTEDPDE 1096

  Fly  1133 -------GSSKFYERKPSQVIASEQLLTPTSSA 1158
                   |.|:.||.:|.....|....|.|:::
  Rat  1097 KGRTGPPGFSEHYELQPLARRRSPSFDTSTATS 1129

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
disp	NP_524734.2	MMPL	<395..1115	CDD:440656	212/749 (28%)
Disp2	NP_001101229.2	MMPL	<448..604	CDD:440656	51/177 (29%)