Protein Alignment disp and Ptchd4

DIOPT Version :9

• Sequence 1: NP_524734.2
• Gene: disp / 44274
• FlyBaseID: FBgn0029088
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: XP_017452249.1
• Gene: Ptchd4 / 301271
• RGDID: 1563020
• Length: 904
• Species: Rattus norvegicus
• Alignment Length: 656
• Identity: 124/656 - (18%)
• Similarity: 225/656 - (34%)
• Gaps: 183/656 - (27%)

  Fly   576 VTSLTTAGAFY---ASYSSSITAIKCFGIFAGTVVVTNYLLMITW------LPASVSIMERLFAT 631
            ::..|.||.|:   ..|:|::..|..|.:..||..|  :.|:..|      ||....:.:.....
  Rat   332 ISIATAAGIFFITDGKYNSTLLGIPFFAMGHGTKGV--FELLSGWRRTKENLPFKDRVADAYSDV 394

  Fly   632 RMSCHHPMSIKLI--------HACKKSINRFCQMFEECITKSIMNYAYLWLLIFGALGASSAVIV 688
            .::.....|:..|        ....:::..|||  ..|:: .::||.|    ||...|   :.:|
  Rat   395 MVTYTMTSSLYFITFGMGASPFTNIEAVKIFCQ--NMCVS-ILLNYFY----IFSFFG---SCLV 449

  Fly   689 FWYPGLQLPEKSHFQLFVSKHPFEVYSSLKQQFWFEKPLQAYENFKMHMHFVWGVQAVDDGDY-- 751
            |   ..||.:..:..:|..|.|...|..       .||             ||....:.||..
  Rat   450 F---AGQLEQNRYHSIFCCKIPSAEYLD-------RKP-------------VWFQTVMSDGHQQT 491

  Fly   752 ----TNPNSYGHLHYDNNF----------NVSSRP---------------AQLWILDFCQ----- 782
                |||  |.| |:..:|          |:..:|               ..|.|.|...
  Rat   492 SHHETNP--YQH-HFIQHFLREHYNEWITNIYVKPFVVILYLIYASFSFMGCLQISDGASIINLL 553

  Fly   783 ----------SVRQQPF--YKETLGMLLPNCFIENLIDYMKRRCIDDMDSTRKDRSPCCD--AQF 833
                      .|:|:.|  |...:|.     ::...::|..       .|.::|....|.  ...
  Rat   554 ASDSPSVSYAMVQQKYFSNYSPVIGF-----YVYEPLEYWN-------SSVQEDLQRLCSGFTAV 606

  Fly   834 PFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKFAEAPRLE--TEDYLGMSGNESAEYSTNGSFTP 896
            .:....:::....:||....|.|.  .|....|.:.|..:  ..|.:         :|..|.
  Rat   607 SWVEQYYQFLKASNISANNKTDFI--SVLQSSFLKKPEFQHFRNDII---------FSRAGD--- 657

  Fly   897 LLVKALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKF--YNVQDTL 959
                      |:|:..|.:|...|...:..:...::..|..|..|     :..::|  :|.....
  Rat   658 ----------ENNIIASRLYLVARTSRDKQKEVIEVLDKLRPLSL-----SKSIRFIVFNPSFVF 707

  Fly   960 S-HDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLG----WQLNILESI 1019
            : |::.......:.|...|||...:...:.|:.:....|.:..|...|.:||    |.:: ::.|
  Rat   708 TDHNSLSVTVPVLIAGFGVLLVLVLTFFLVIHPLGNFWLILSVTSIELGVLGLMTLWNVD-MDCI 771

  Fly  1020 AVSTAIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASNILPY 1084
            ::     |.:.::|::.|.:....:...:.||:...::.|..::.       ..|..:..||..:
  Rat   772 SI-----LCLIYTLNFAIDHCAPLLYTFVLATEHTRTQCIKSSLQ-------EHGTAILQNITSF 824

  Fly  1085 IQIGVFLVVVMIVSWFYATFFLMSLLRVAGP---QHGFLELKWPLW------SKRSSGSSKFYER 1140
            : ||  ||.::.|. ...||.|...|.:.|.   .|.|:.|  |::      ||:.....|..:|
  Rat   825 L-IG--LVPLLFVP-SNLTFTLFKCLLLTGGCTLLHCFVIL--PVFLTFFPPSKKHHKKKKRAKR 883

  Fly  1141 KPSQVI 1146
            |..:.|
  Rat   884 KEREEI 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
disp	NP_524734.2	Patched	<444..1111	CDD:280598	112/610 (18%)
		MMPL	457..627	CDD:304422	15/59 (25%)
		TM_PBP1_branched-chain-AA_like	964..>1109	CDD:294309	29/148 (20%)
Ptchd4	XP_017452249.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348802
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840