Protein Alignment disp and ptr-3

DIOPT Version :9

• Sequence 1: NP_524734.2
• Gene: disp / 44274
• FlyBaseID: FBgn0029088
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: NP_493718.2
• Gene: ptr-3 / 173426
• WormBaseID: WBGene00004218
• Length: 927
• Species: Caenorhabditis elegans
• Alignment Length: 1003
• Identity: 188/1003 - (18%)
• Similarity: 341/1003 - (33%)
• Gaps: 316/1003 - (31%)

  Fly   243 FFCDSSPRKEYSHFVVQRIGPNATDSLFDLNGLLAMCQLQDQI--------------TEVP-SYR 292
            ||.:....|....|:..::|.|          :|.:.||.|.:              ::.| ::.
 Worm    82 FFNNHGEPKAIYAFITSKVGDN----------MLGISQLNDTVHVLDTISRDFYLKTSQGPKNFE 136

  Fly   293 AFCEPEMLTTECCRPWSLPNYAAMLANKSSCFDLTTEDVTSLHTLLLGCYEY----FHDLKMDNH 353
            .:|....|..|..:.:    |:.||.:.....|.:..|:....|.:||...|    |..:|:...
 Worm   137 EYCSGFCLLNEPVKHF----YSGMLISGQHGTDFSHLDLGYPITTVLGTKLYMDPNFFGVKVTTS 197

  Fly   354 CNEI------------PHCR-APEECKRLNIVFNVLNFLTDF-SFIKSNDSNVYLKYAMIFIPVA 404
            .|::            .|.: .|...:.:::|  ||.|.::. ..:...|...|
 Worm   198 NNKVESIADGNTKLFGDHTKQEPNNIREVSLV--VLQFRSELGDEVTPEDLRNY----------- 249

  Fly   405 QSNRLLPLFHEWEDVELINELV--------EVVAMDLGLENELFNELLLTDVWLVSLGGTFVMAS 461
             .:::|...|:....|.||..:        |:|...|.|...|   ::...:..|....|||:::
 Worm   250 -EHQILDYIHDEYQSEHINVYILTDSYITEEIVRAGLTLLPFL---VIGFTIMAVFSSITFVVSA 310

  Fly   462 VW---LYTGSAFITLMSCV----AICFSLGLAYFFYAIVLEFEFFPYMNLLAVV--VIIGIGADD 517
            .:   |......:.:|:||    |...||| |.||..       |.:.::|.|.  :::.||.||
 Worm   311 YYTKQLNFYKPILAVMACVCPFMACGASLG-AMFFIG-------FRFGSILCVTPFLVLAIGVDD 367

  Fly   518 VFLFLKIWHCVLTERFSNRCTLTTQSQSALPTLENSDHTESLENIMALTMRHAAASMFVTSLTTA 582
            .:|....|         .|.|...:..:...::     ...|:|.:.........|:.:|::|.|
 Worm   368 SYLMANAW---------QRITCHRRKHARFESV-----NVELKNRITEMFIETGPSITITTITNA 418

  Fly   583 GAFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWLPASVSIMERL-FATRMSCHHP-------- 638
            .||....::....|:.|.|.....|:|:::..||:..|.::::.|. ....:....|
 Worm   419 LAFGIGATTPAAEIQLFSIGNALAVITDFVFTITFYGALMAVVGRYEIEQELKTQKPLPESESPS 483

  Fly   639 -------MSIKLIHACKKSINRFCQMFEECITKSIMNYAYLWL--LIFGALGASSAVIVFWY--- 691
                   |....:..||     |.:|... :.|.:.|   .|:  ::.|.|.      |:||
 Worm   484 ETSSTGSMRSSELDDCK-----FRRMIAN-VCKFLTN---TWVCSVVLGLLA------VYWYICI 533

  Fly   692 -----------PG-LQLPEKSHFQLFVSK--HPFEVYSSLKQQFWFEKPLQAYENFKMHMHFVWG 742
                       |. |.|.|.:..::|..:  |....||:                       .|
 Worm   534 VGTVNIKSELSPNKLFLAESNIVEIFKQRKSHIIPYYSA-----------------------CW- 574

  Fly   743 VQAVDDGDYTNPNSYGHL---------------HYDNNFNVSSRPAQLWILDFCQSVRQQPFYKE 792
            |...:.||..|||....|               .|...|         |:.|:      :.|.|:
 Worm   575 VLVENPGDINNPNQRAKLEELIESFEALPSANGRYSTKF---------WLRDY------EDFLKQ 624

  Fly   793 TLGMLLPNCFIENLIDYMKRRCIDDMDSTRKDRSPCCDAQFPFEPHIFEYCLPQSISNMYDTTFF 857
            :..:.||                  |:....:                |..:..:::.....|..
 Worm   625 SEEIDLP------------------MEEEEDE----------------ELAIQFTVNGSQVVTPS 655

  Fly   858 RPGVAGPKFAEAPRLETEDYLGMSG----NESAEYSTNGSFTPLLVKALVIEFESNVAYSTIYAN 918
            :|...|.:..:.  ||..::....|    |||....:....|.....:.::::.:.       |.
 Worm   656 QPFGQGNELRQF--LEWPEFSFWKGFIQVNESTYQMSKFLVTTAYHGSDLVDWSNR-------AK 711

  Fly   919 IRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLSHDTFVAICLAM--AASL----AV 977
            :...:.||..  |.:.|:    |....:..|.||.::.:|:|.   |||..|:  .||:    |:
 Worm   712 LLNEWRSVAD--QDKFKS----LNVTVYEEDAKFLDLIETMSP---VAIQSALWTFASMFLVAAL 767

  Fly   978 LLCFTVNILISIYAVLTVSLSIFNTVAVLILLGWQLNILESIAVST---AIGLAVDFSLHYGIHY 1039
            .:.....:.::.:::|:.||.:|.      ::.|....|:.|.:|.   :||.:||...|...|:
 Worm   768 FISHPPTLFVATFSILSTSLGVFG------IMSWWGADLDPIMMSATVMSIGFSVDIPSHVSYHF 826

  Fly  1040 RM-----SPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASNILPYIQIGVFLVVVMIVSW 1099
            ..     |.::.||   |..:..:..|...|:.:|.|.                       ::|.
 Worm   827 YQTAKDTSDIRRRL---QMTIEAVGFPIFEASLSTSLC-----------------------VMSL 865

  Fly  1100 FY-----ATFF--LMSLLRVAGPQHGFL 1120
            |:     |..|  .|.|:.|.|..||.|
 Worm   866 FFVDLNMAQIFAKCMLLVVVIGMVHGML 893

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
disp	NP_524734.2	Patched	<444..1111	CDD:280598	139/750 (19%)
		MMPL	457..627	CDD:304422	40/178 (22%)
		TM_PBP1_branched-chain-AA_like	964..>1109	CDD:294309	34/165 (21%)
ptr-3	NP_493718.2	Patched	48..904	CDD:308203	188/1003 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6166
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950