Protein Alignment disp and ptchd3

DIOPT Version :9

• Sequence 1: NP_524734.2
• Gene: disp / 44274
• FlyBaseID: FBgn0029088
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: XP_031759849.1
• Gene: ptchd3 / 100494800
• XenbaseID: XB-GENE-950407
• Length: 982
• Species: Xenopus tropicalis
• Alignment Length: 936
• Identity: 186/936 - (19%)
• Similarity: 335/936 - (35%)
• Gaps: 290/936 - (30%)

  Fly   309 SLPNYAAMLANKS-----SCFDLTTEDVTSLHTLLLGCYEYFHDLKMDNHCNEIPHCRAPEECKR 368
            |.|.:..||..||     |||.|.......|..:.....|:|....:..|.:..        ||:
 Frog   229 SFPQHLQMLQLKSVQVKKSCFFLVQFPPQCLSPVSPALIEHFLQKLVGPHADIF--------CKK 285

  Fly   369 LNI-------------VFNVLNFLTDFSFIKSNDSNVYLKYAMIFIPVAQSNRLLPLFHEWEDVE 420
            ..:             :|..:.:.|..|..|..:.:              :.|.:|.|.....|.
 Frog   286 FFVFFLRWAGLQEQYYLFIFVYYYTSVSLQKQLEED--------------AKRAMPFFSVTFIVT 336

  Fly   421 LINELVEVVAMDLGLENELFNELLLTDVWLVSLGGTFVMASVWLYTGSAFITLMSCVAICFSLGL 485
            ::..::..|... .:.|:         :| |:|.|.       :..|.|.:|....:.:|   |.
 Frog   337 ILFSVLSCVRCH-NVRNK---------IW-VALFGV-------ISPGLAILTSFGLLLMC---GA 380

  Fly   486 AYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTERFSNRCTLTTQSQSALPTL 550
            .:...|:...|            :|:|.|.|::|:.:..|     ::...|.|
 Frog   381 PFAITAVNAPF------------LILGAGVDNMFIIISCW-----QQTKMRAT------------ 416

  Fly   551 ENSDHTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVTNYLLMI 615
                    ||..||.|.:.||.|:.:|:||...|||....:...:::.|.|:|||.:|..|:..|
 Frog   417 --------LEERMAETYQEAAVSITITTLTDVLAFYIGIMTHFPSVQSFCIYAGTALVFCYVYCI 473

  Fly   616 TWLPASVSIMERLFATRMSCHHPMSIKLIHACKKSINR---FCQMFEECITKSIMNYAYLWLLIF 677
            |:..|.:::..:|                    ::.||   .|....: ..:|..|..|....:.
 Frog   474 TFFGAVLALNGKL--------------------ENDNRHWFICVKVND-TEESGQNTMYQMCCLG 517

  Fly   678 GALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEV-----YSSLKQQFWFE----------KPL 727
            |:...|..:.:                   :||..|     |.......|.:          ..:
 Frog   518 GSFETSEGIEI-------------------EHPVTVFFHKYYGVFLTNQWTKLLTVVVYLGYLAI 563

  Fly   728 QAYENFKMHMHFVWGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKE 792
            ..|..||:.       ..||...:.|.|||...:|.|.        .|:...:...|
 Frog   564 SIYGCFKLQ-------GGVDIQKFPNDNSYLSQYYTNE--------ALYFAGYGPRV-------- 605

  Fly   793 TLGMLLPNCFIENLIDYMKRRCIDDMDSTRKDRSPCCDAQFPFEPHIFEYCLPQSISNMYDTTFF 857
               |::    :.:.|.|.:.:...:::|                      |:.:..:|.|
 Frog   606 ---MVV----VTSEIAYWEPQTSKEIES----------------------CMQKLENNSY----- 636

  Fly   858 RPGVAGPKFAEAPRLETEDYLGMSGNESAEYSTNGSFTPL-LVKALVIEFESNV--AYSTIYANI 919
                ...||.|: .|.|.:::..:.|.|. .:.:|....| ::.|...||:.::  ..:.|.|:
 Frog   637 ----VDKKFTES-WLRTYEHMSKALNVSI-ITKDGFMNNLDIIFAYFAEFKQDIDKEGNKIKAS- 694

  Fly   920 RQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLSHDTFVAICL---AMAASLAV---L 978
            |.|.:::.....:..:....:|:|...:.::..:     :.|..|  |||   |:....||   :
 Frog   695 RFFVQTINVVGAIDERNMATQLRGIAASCNIPLF-----VYHPIF--ICLDRYALIIQSAVQNMI 752

  Fly   979 LCFTVNILISIYAVLTVSLSIFNTVAVL-ILLG-------WQLNILESIAVST---AIGLAVDFS 1032
            :.|.|.:::|:..:.....|::.|.|:. |::|       |::| |:||::.|   .||.:||||
 Frog   753 VAFVVMLVVSLLFIPNPLCSLWVTFAIASIIVGVAGFMAFWRVN-LDSISLITLVICIGFSVDFS 816

  Fly  1033 LHYGIHYR-MSPVKERLAATQFVLSRIIG-PTVMAATTTGLAGGIMMASNILPYIQIGVFLVVVM 1095
            .|  |.|. .|..||:..........::| |.|..|.:|.|  |::..|               :
 Frog   817 SH--IAYACFSSKKEKTEERVIDALHVLGYPIVQGALSTIL--GVVALS---------------V 862

  Fly  1096 IVSWFYATFFLMSLLRVA-GPQHG------FLE-LKWPLWSKRSSGSSKFYERKPSQVIASEQLL 1152
            ..|:.:.|||.::.|.:| |..||      ||. :..|.||..|       :.||.::  |.|
 Frog   863 AESYIFKTFFKLTCLVIAFGVLHGLVFIPVFLTIIACPRWSHVS-------KVKPLKI--SHQ-- 916

  Fly  1153 TPTSSAIVELANSETHELESLNSNSL 1178
              .::.:.||.....:.:.|:..::|
 Frog   917 --PANIMTELERQRENPIRSVQKDNL 940

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
disp	NP_524734.2	Patched	<444..1111	CDD:280598	141/706 (20%)
		MMPL	457..627	CDD:304422	39/169 (23%)
		TM_PBP1_branched-chain-AA_like	964..>1109	CDD:294309	45/163 (28%)
ptchd3	XP_031759849.1	Patched	95..898	CDD:355433	174/879 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910