Protein Alignment disp and disp3.2

DIOPT Version :9

• Sequence 1: NP_524734.2
• Gene: disp / 44274
• FlyBaseID: FBgn0029088
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: XP_031761685.1
• Gene: disp3.2 / 100491297
• XenbaseID: XB-GENE-1033849
• Length: 1328
• Species: Xenopus tropicalis
• Alignment Length: 1322
• Identity: 244/1322 - (18%)
• Similarity: 431/1322 - (32%)
• Gaps: 446/1322 - (33%)

  Fly   132 EHHDVAQKMMQFKKRLKATSSPSPNLGFDTWIGDSGVFRDYEITNDSASSSLEPTRRT--EQIEY 194
            ::|..:|:.......||:.        |.||    |..|     .|.|..:.|..:|.  ||::.
 Frog    97 QNHKSSQRFDALTLALKSQ--------FGTW----GRNR-----RDVADLTSETLQRLIFEQLQQ 144

  Fly   195 GH-NTTSVDEEEHQQRVQTKKSTWRLLKQAATLPTDGWADMHRRQPIEGFFCDSSPR------KE 252
            .| |.:........:|..|:.:|.:.:....|..:...|....|.|......||:..      :.
 Frog   145 LHQNASQQGTTVRVKRSSTRHNTTQSINDTKTETSVCIAGNQSRHPRGDSKRDSAVNFVTPITQS 209

  Fly   253 YSHFVVQRI---GPNATDSLFDLNGLLAMCQLQDQITEVPSYRAFC-EPEMLTTE--------CC 305
            ..|:.::.|   ..::.:::|....|:.:..::.:|.:.|.:|.|| :|.....:        |.
 Frog   210 RVHWRIELIFLARGDSENNIFTKERLMTIHSIERKIMDHPHFREFCWKPHETLKDLPLGSYSYCS 274

  Fly   306 RPWSLPNY------------------------AAMLANKSSCF------DLTTEDVTS---LHTL 337
            .|.||..|                        :..||.....|      .||||::.|   ...:
 Frog   275 PPSSLLTYFFPTEKGGKIYYDGMGQDLADVYGSLKLAMTHPEFYWYVDEGLTTENLKSSLLRSEI 339

  Fly   338 LLGC----YEYFHDLKMDNHCNEIPHCRAPEECKRLNIVFNVLNFLTDFSFIKSNDSNVYLKYAM 398
            |.|.    |....|...:.|            .|..|.|.:.:|.|:     |.:.|.|.:.|.
 Frog   340 LFGAPLPNYYSVEDRWEEQH------------RKFQNFVTSYINILS-----KESTSKVQVLYG- 386

  Fly   399 IFIPVAQSNRLLPLFHEWEDVELINELVEVVAMDLGLENELFNELLLTDVWLVSLGGTFVMASVW 463
                               ..:|.:..|...          ||    .|:.|..:..:.:...|:
 Frog   387 -------------------GTDLFDYEVRTT----------FN----NDMLLAFISSSCIAVLVY 418

  Fly   464 LYTG-SAFITLMSCVAICFSLGLAYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHC 527
            :.|. |.|::.....:|..|..:|.|.|.:..|.::...:|.:|..||:|||.||||:|:.
 Frog   419 ILTSCSVFLSFFGIASIGLSCLVALFLYHVAFEKQYLGILNGVAAFVIVGIGVDDVFVFIN---- 479

  Fly   528 VLTERFSNRCTLTTQSQSALPTLENSDHTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSS 592
                                 |...::..|..:..|..|::.|..:.|.||||||.|:.|:..|.
 Frog   480 ---------------------TYRQANQFEDPQLRMIHTVKTAGKATFFTSLTTASAYAANIFSQ 523

  Fly   593 ITAIKCFGIFAGTVVVTNYLLMITWLPASVSIME-RLFATRMSCHHPMSIKLIHA---------- 646
            |.|:..||:|...:|...::.::..:||::.|.. .:.....|||...|.|.:..
 Frog   524 IPAVHDFGLFMSLIVSCCWVAVLFVMPAALGIWSIYISPLESSCHSNCSEKCLRGNSLDIYEDLL 588

  Fly   647 -----CKKSINRFCQMF----------EECIT------------------------------KSI 666
                 ..:|:....|..          :|.:|                              ::|
 Frog   589 LAQDPPSRSVQSTAQYIDDDIPLLTVEDESVTLEYEDVPLVSVHPVEQKTGRDRRDHLIWWLQNI 653

  Fly   667 MNYAYLWLLIFG---ALGASSAVIVF-------WYPGLQLP----EKSHFQLFVS-KHPFE---- 712
            ::::.||....|   .:|...||::|       .:|..:.|    ..::.||.:. |:...
 Frog   654 LHHSVLWTTAKGRYITIGCFVAVLIFSIVFATRLHPASRAPILFRPDTNIQLLLDLKYNLSAEGI 718

  Fly   713 ---VYSSLKQQFWFEKPLQAYENFKMHMHFVWGVQAVDDGDYTN-----PNSYGHLH-------- 761
               ..|.|.|    |||.....|.:.      ..:....|.::.     .|| .::|
 Frog   719 SCITCSGLFQ----EKPHSLQNNIRT------SSEKKKRGSFSQLSARAANS-DNVHQDLQRTVY 772

  Fly   762 ------------YDNNFNVSSRPAQ-----------------------LWILDFCQSVRQQPFYK 791
                        |..::|.||.|..                       .|.|..|.|
 Frog   773 ITRCKLEERITIYRLSYNASSIPPWQPVLPGEDDVSTFQVYKVPYGNFTWKLTACMS-------- 829

  Fly   792 ETLGMLLPNCFIENLI-------------DYMKRRCIDDMDSTRK------DRSP----CCDA-- 831
             |||:....|..:.::             |:.......:...|||      .::|    .|.:
 Frog   830 -TLGLNRGMCPKKWMLTSTACDTKRGWKFDFSFYAAEKEQHYTRKLYFSLIHKNPSHGKICSSPA 893

  Fly   832 ---------------------------QFPFEPHIFEYCLPQSISNMYDT---TFFRPGVAGPKF 866
                                       .:.|.|.:...|...::..:.||   .|...|:.|...
 Frog   894 NCLGPDEANKGYFYVPIDKGSRGKLSLTYGFNPCLNTGCGKPAVRPLVDTGAMVFVVFGIKGVNR 958

  Fly   867 AEAPRLETEDYLG-----------------------MSGN------ESAEYSTNG----SFTPLL 898
            ..||.......||                       ::.|      ..|:...:|    ||..:|
 Frog   959 TRAPDNHVLGELGKVIYDDKFDLFKEIGHLCRLCKVIASNLELVKRGGAQCLPSGYSISSFLQML 1023

  Fly   899 -----------------------VKALVIEFESNVAYSTIYANIRQF-----YESVEHWFQMQLK 935
                                   :|...:::.|....||.|.....|     |...|.:.|.||.
 Frog  1024 HPECKNIPEPNLLPGQLSHGAVGLKDAKVQWISMAFESTTYKGKSSFQTYKDYLKWESFLQEQLL 1088

  Fly   936 TAPPE--LQGGWFTSD------LKFYNVQDTLSHDTFVAICLAMAASLAVLLCFTVNILISIYAV 992
            ..|.:  |:.|:.|.:      ::...||..|:     .:.|::...:..:..||.::|:.:..:
 Frog  1089 LLPADSALKHGFQTCEHWKQIFMEIVGVQSALN-----GLILSLLICVGAVAIFTTHVLLLLPVL 1148

  Fly   993 LTVSLSIFNTVAVLILLGWQLNILESIAVSTAIGLAVDFSLHYGIHYRMSPVK-------ERLAA 1050
            ||:...:...||::..|||::..:|:|::|..:|.:||:.:|....|.::..|       :.||.
 Frog  1149 LTILGVVCLVVAIMYWLGWEMGAVEAISLSILVGSSVDYCVHLVEGYLLAGEKLPQHLNEDPLAC 1213

  Fly  1051 TQF---VLSRIIGPTVMAATTTGLAGGI-MMASNILPYIQIGVFLVVVMIVSWFYATFFLMSLLR 1111
            .|:   ...|.:|..::::..|.:...| :....|.|:.:.|..:.:...:|..|......:||.
 Frog  1214 RQWRALEAVRHVGVAIVSSALTTIISTIPLFFCIIAPFAKFGKIVALNTSISIVYTLTVSTALLS 1278

  Fly  1112 VAGP------QHGFLELKWPLW 1127
            :.||      :..|  ||..||
 Frog  1279 IMGPCTFVRSRTSF--LKATLW 1298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
disp	NP_524734.2	Patched	<444..1111	CDD:280598	169/928 (18%)
		MMPL	457..627	CDD:304422	46/171 (27%)
		TM_PBP1_branched-chain-AA_like	964..>1109	CDD:294309	32/155 (21%)
disp3.2	XP_031761685.1	COG1033	<357..>553	CDD:223964	61/271 (23%)
		COG1033	<1158..>1278	CDD:223964	27/119 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I10218
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000