Protein Alignment tio and tshz3b

DIOPT Version :9

• Sequence 1: NP_001260679.1
• Gene: tio / 44272
• FlyBaseID: FBgn0028979
• Length: 1024
• Species: Drosophila melanogaster
• Sequence 2: NP_001182336.1
• Gene: tshz3b / 565811
• ZFINID: ZDB-GENE-100319-2
• Length: 1147
• Species: Danio rerio
• Alignment Length: 1121
• Identity: 214/1121 - (19%)
• Similarity: 356/1121 - (31%)
• Gaps: 381/1121 - (33%)

  Fly   104 AAYLAAAQQNHLLLTNPLAAAASLVQHATQQAVV-----------EGEVESPALDFSRKRPKSHG 157
            |||:....:...||...:....|.::.......|           .|..:||..|||.....|..
Zfish    13 AAYVPEELKEAALLDEDVEGEDSALEEEPAMKYVCQDKDLLLKDRPGFHDSPPADFSSHEMDSES 77

  Fly   158 DDDQEEDQEQD--------QEQEQEQEPDHDVQCDNGPLDLSVSTGKRQESVSPPARKIPRSISA 214
            ...:..|:..|        :|....:||...:...:..:..:.:|...:|: :|........:.|
Zfish    78 HLSESSDRMSDFESASVKNEEDSSAKEPLTSLSSTSSMMMTTTATPSSEEA-TPLGPDSLEQMKA 141

  Fly   215 DYKSPLPPGSW---------MPPINP----------YLAAVAAKTGGLGYSKLAPSEASKALEKM 260
            .|.|.|....|         .||..|          ..::.:..:||..:.:.|   .:|.|:.:
Zfish   142 IYTSFLTNSYWSSLNLNLSQQPPEKPPRSHSSSSSSSSSSSSCGSGGYDWHQTA---VAKTLQNV 203

  Fly   261 TE-MSRLETSPTAARSLGATSSVGAGVPAGASSNSGGRHSAWQSHWLNKGADTAKDVFKCVWCKQ 324
            :: .||| ..|.:..:|.:|..:..                 ||..|.....|....|:|..|..
Zfish   204 SQNQSRL-LHPASEPNLFSTVQLYR-----------------QSTKLYGSIFTGASKFRCKDCSA 250

  Fly   325 SFSTLANLTAHMKETQHCGVQIPSPLPTGGVGTPSAPPPTRLATSASNSACSSSSSSTSSSSNSS 389
            ::.||..||.||.||.|                                 ....:..|.|.....
Zfish   251 AYDTLVELTVHMNETGH---------------------------------YRDDNHETDSEGTKR 282

  Fly   390 KSELNMLIKETMPLPRKLVRGQDVWLGKGAEQTRQILKCMWCGQSFRSLAEMTSHMQETQHYTNI 454
            .|:         |..|.|:..:      |.|..:::||||:||.||.||.:::.||.:|:||..:
Zfish   283 WSK---------PRKRSLLEME------GKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKV 332

  Fly   455 ISQE-------QIIS---WKSGDERERP----TNTGVPSTSTAAPSSPSCTAPS----------- 494
            ..:|       :|||   .::..|.|.|    :|.|.|..|.:.|:......|:
Zfish   333 PLKEPVTPVAAKIISSARKRAPIELELPSSPDSNGGTPKPSLSDPNDLLQKTPNPYITPNNRYGH 397

  Fly   495 -------------VSAVLTCKVCDQAFGSLKELSTHMAQKSHY--------------KESPAPSA 532
                         .|.:|.|..|..:..:|:||:.||....|:              .||.:.:|
Zfish   398 QNGASYAWQFESRKSQILKCMECGSSHDTLQELTAHMMVTGHFIKVTNSAIKKGKPIMESMSTTA 462

  Fly   533 SPPAAGTGNPKRGRQNRNEKRKKSLPV-----------------------------RKLLELERS 568
            ..|..           .||.:.:|:|:                             .|.:|..|.
Zfish   463 PNPIL-----------TNEDKVQSVPLAATAFSPPPPAPPPPSISPAIMPMEIKKEEKEVECTRE 516

  Fly   569 GSNSSLDSALKPLRDFAAATKITCEKCGSKIETALFVEHIRKCLGESIPIPPRRSNAGVDRLPSP 633
            .:|:         :|..||...|.||.....:.....|.                    |...||
Zfish   517 TNNN---------KDKKAAESETDEKFEVSSKYPYLTEE--------------------DLEESP 552

  Fly   634 SLGLGAEKPPSVLNALEQLIEKSFESRTSRTMTHGGY-------------------SEAGTPL-- 677
            ..|.      .:|.:||..:..:.....:.|.:.|||                   |...:||
Zfish   553 KGGF------DILKSLENTVTSAINKAQNGTPSWGGYPSIHAAYQLPNIMKLSLRNSGKSSPLKY 611

  Fly   678 ---GASILKRLGIEDSSDYTKPLM---DAQAMHLLRSSFASRDRSASE-SSSASRVESSYTPDRQ 735
               |..:|       |...::||:   ..|.....:::|.:.:....: :...::||........
Zfish   612 MFSGEELL-------SPTKSQPLISPPSCQTSPFPKNNFHAMEELVKKVTEKVAKVEEKMRDPGA 669

  Fly   736 QATPHKSPDTPAPPPPPPPTIKAEPLEAEPLVGCDREGCSPRQQIQVKKEFSMEACRESPRSVSK 800
            :::|.:. .||:|                         ||        .:....|..|||:....
Zfish   670 RSSPLRR-TTPSP-------------------------CS--------SDAGESARGESPKERRG 700

  Fly   801 SPAPQTERSPPDNGSLLALNSMFDQLSGVENSGNNNSGHCFNN--NNSCSSVS------AQKPKA 857
            :..|:|     :.|.:....|..|.|:  :.|..|.:.|....  :..|||.:      .::|..
Zfish   701 AKTPET-----NGGGITHKESNGDALT--KESLENGTDHVVKTPVSTLCSSTAIITDHPPEQPFV 758

  Fly   858 HPLAALQKLCE------------TTDPPSTGLRSASS-AGSSTASATLPS--ANGNDLV--AFSW 905
            :||:|||.:..            :.||.|...:.::| |..:..:|:.||  ...||.:  .|..
Zfish   759 NPLSALQSVMNVHLGKAAKPALPSLDPMSMLFKMSNSLAEKAAVAASTPSQTKKTNDHLDRYFYH 823

  Fly   906 ACNEAVLSASNG--------GSAGDSS---------------IIKCSYCDTPFASKGAYRHH-LS 946
            ..|:..:..:.|        |||..||               :.|.|.....|.|....|.: ||
Zfish   824 INNDQPIDLTKGKSDKSNSLGSAALSSSTSTPTSISPSSTITMAKASSAVASFMSNSPLRENALS 888

  Fly   947 KVHFVKDAGEDSPRLKSPAVQSPRSMPLASPRRSASRSPATGSQQPPPSPTISPYDE-------- 1003
            .:         |..|::  :....:...::|...:.||...|| .|..|..|||..:
Zfish   889 DI---------SDMLRN--LTENHACKSSTPTSLSERSDIDGS-TPEESEEISPAQKRKGRQSNW 941

  Fly  1004 SPQSKFLKYTELAKQL 1019
            :||...:...:.|..|
Zfish   942 NPQHLLILQAQFASSL 957

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tio	NP_001260679.1	zf-C2H2_2	<317..>344	CDD:289522	12/26 (46%)
		C2H2 Zn finger	319..341	CDD:275371	10/21 (48%)
		C2H2 Zn finger	428..450	CDD:275371	11/21 (52%)
		zf-C2H2_4	927..949	CDD:290605	7/22 (32%)
tshz3b	NP_001182336.1	C2H2 Zn finger	245..267	CDD:275371	10/21 (48%)
		C2H2 Zn finger	306..328	CDD:275371	11/21 (52%)
		homeodomain	935..1003	CDD:238039	4/23 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580303
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	101	1.000	Inparanoid score	I4973
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6467
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12487
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.080