DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment xmas and SAC3C

DIOPT Version :9

Sequence 1:	NP_001356948.1	Gene:	xmas / 44271	FlyBaseID:	FBgn0286809	Length:	2079	Species:	Drosophila melanogaster
Sequence 2:	NP_851016.1	Gene:	SAC3C / 824604	AraportID:	AT3G54380	Length:	406	Species:	Arabidopsis thaliana

Alignment Length:	462	Identity:	118/462 - (25%)
Similarity:	187/462 - (40%)	Gaps:	98/462 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 SALQSGWRNEYGSGKPIKKPQNGSSGSGGSSMLPAIPVGPATAPVSRDRTPAQLRDLENMMRRPA 168
            |:..|...|.||:.:....|:.||.|....|....     :.||..|:          |......
plant     9 SSSSSRVSNTYGNRQFSDNPRTGSGGGVNESFQRR-----SDAPHKRN----------NEKDESK 58

  Fly   169 HTSEEKFSVLDARDKLLRLNRTQHKLSGATQGHCADMCPEKERVLREFQRQVAYYELQPGSDELI 233
            |..|:...|                  ....|.|:.||||:|||.||..|.:|.:|...|:....
plant    59 HKDEDPADV------------------SLIVGTCSSMCPERERVTRERLRDLAVFERLYGNPSKS 105

  Fly   234 CHERALKQYSR--SSADQET----PLPHELRNETALHMTMSYLMHEIMDISERQDPQSHMGDWFH 292
            ..|.|:|::.|  |:||.:.    |||       .|..|:.||:..:       |.:.|..:..|
plant   106 STEIAVKKFCRTLSAADVQASDVRPLP-------VLEETLRYLLSLL-------DSKEHPFEVVH 156

  Fly   293 -FVWDRTRSIRKEITQQELCSLGAVKLVEQCARFHIHCAARLVDADPSVFDS--KINAENLTKCL 354
             |::|||||||::::.|.|.:...:.|.|:..:||:....||.....:...|  .:|.|.|.|.|
plant   157 DFIFDRTRSIRQDLSIQNLANERVIYLYEEMVKFHVISHERLQSCSGTSISSMHHLNMEQLAKTL 221

  Fly   355 QTLKYMYHDLRIKGVPCPKEAEFRGYIVLLNLADAN-------FLWDIGQLPAELQSCPE---VR 409
            .:|..:|...|........|||||...|||:|..::       .|| ..:|...|....|   ||
plant   222 TSLYNIYDANRKPDYIYENEAEFRSLYVLLHLNPSSGVMGEPLSLW-FRKLTFALVKSKEICFVR 285

  Fly   410 QAIQFYLALQDTNFVRFFQLLADKDTSYLSACILVNYFTRLRVLGLHRL------IQAYRSPRKD 468
            ..::.|   :..|:..|....|.:.| ||..||..::...:|::.:..:      :|.|
plant   286 NLLRLY---RMGNYKNFLSRTASEAT-YLQYCISEHHIREMRLVAVQYINNVCYKLQPY------ 340

  Fly   469 EVSSLPLSYIAELLSFASEQEAADFVQHYGLQ--INEAGRVVL----SRMHTVETEYKLPRQYEL 527
                 ||..:::.|.. .|.:........||:  .:..|..||    |...:.|.::|:   |:|
plant   341 -----PLLRLSQNLKM-KELDVESLCHECGLETCTDPDGFTVLPVKQSTFRSPEDKFKV---YDL 396

  Fly   528 VEVKRVK 534
            :.::|:|
plant   397 IGIERIK 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
xmas	NP_001356948.1	RRM_XMAS2	12..82	CDD:240903
		SAC3_GANP	200..503	CDD:335312	91/329 (28%)
		DUF5401	<638..>827	CDD:340095
SAC3C	NP_851016.1	CSN8_PSD8_EIF3K	126..349	CDD:305176	65/252 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	123	1.000	Domainoid score	I1830
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593971at2759
OrthoFinder	1	1.000	-	-		FOG0003569
OrthoInspector	1	1.000	-	-		otm3088
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12436
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.020