DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment xmas and SPCC70.06

DIOPT Version :9

Sequence 1:	NP_001356948.1	Gene:	xmas / 44271	FlyBaseID:	FBgn0286809	Length:	2079	Species:	Drosophila melanogaster
Sequence 2:	NP_588540.1	Gene:	SPCC70.06 / 2539567	PomBaseID:	SPCC70.06	Length:	458	Species:	Schizosaccharomyces pombe

Alignment Length:	411	Identity:	116/411 - (28%)
Similarity:	178/411 - (43%)	Gaps:	64/411 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 PAQLRDLENMMRRPAHTSEEKFS-VLDARDKLLRLNR------------TQHKLSGATQGHCADM 205
            |....|..:..:|.|..:  :|| .|||..:.|:..|            |..:.|....|.|..|
pombe    15 PKPSLDRSDSTKRAARAA--RFSTTLDANFQALKKKRKDEQESFQAKQSTNWEKSSVLVGTCRQM 77

  Fly   206 CPEKERVLREFQRQVAYYELQPGSDELICH-ERALKQYSRSSADQETPLPHELRNETALHMTMSY 269
            |||.|...|:.|..:..|||.|.|.:  .| ..|:|.|.|.:|.:...||.::|..:.|..|:.|
pombe    78 CPEFELEERKLQHAIHPYELDPVSKQ--AHPSLAVKAYHRPAAGKGPILPSDVRPPSILKNTIDY 140

  Fly   270 LMHEIMDISERQDPQSHMGDWFHFVWDRTRSIRKEITQQELCSLGAVKLVEQCARFHIHCAARLV 334
            |...|:|....::..:       ||.||||::|::.:.|...|..:|...|..|||||.....|
pombe   141 LFKVILDRYSLREAHA-------FVRDRTRAVRQDFSVQSSFSQDSVYCHELIARFHIISLHEL- 197

  Fly   335 DADPSVFDSKINAENLTKCLQ---TLKYMYHDLRIKGVPCPKEAEFRGYIVLLNLADANFLWDIG 396
             |....|..:...|.|:|.::   ||..:|..:.::...|..|||||.|:|||:|.|.:...|..
pombe   198 -AHTPNFSRQQEIEQLSKSMEILYTLGQLYDYMHLRKEHCTHEAEFRAYMVLLSLGDPSVGLDTL 261

  Fly   397 QLPAELQSCPEVRQAIQFYLALQDTN-------------------------FVRFFQLLADKDTS 436
            ..|..:...|.|:.:::.|...|..|                         :.|||::.:....|
pombe   262 SWPDFVFKKPIVKTSLKLYSLAQRNNHTITTSNSISLSLVSSFNTEATSNLYTRFFKIASSFRVS 326

  Fly   437 YLSACILVNYFTRLRVLGLHRLIQAYRSPRKDEVSSLPLSYIAELLSFASEQEAADFVQHYGLQI 501
            ||..|:|..:...:|...|..:.:.|.|..    |::|...:.::|:..||.|.....:.:||:|
pombe   327 YLMGCLLDLFVPSIRTGALKAMKKCYLSAH----SNIPFKDLMKILAATSEDELVQCCKMHGLKI 387

  Fly   502 NEAGR----VVLSRMHTVETE 518
            ...|.    |||:| .||.||
pombe   388 EYIGEQPSAVVLNR-KTVITE 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
xmas	NP_001356948.1	RRM_XMAS2	12..82	CDD:240903
		SAC3_GANP	200..503	CDD:335312	94/331 (28%)
		DUF5401	<638..>827	CDD:340095
SPCC70.06	NP_588540.1	SAC3_GANP	124..369	CDD:281402	67/257 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	142	1.000	Domainoid score	I1184
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003569
OrthoInspector	1	1.000	-	-		otm47398
orthoMCL	1	0.900	-	-		OOG6_103177
Panther	1	1.100	-	-	O	PTHR12436
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1280
SonicParanoid	1	1.000	-	-		X2919
TreeFam	0	0.000	Not matched by this tool.
	8	7.940