Protein Alignment sut2 and HXT5

DIOPT Version :10

• Sequence 1: NP_524732.1
• Gene: sut2 / 44269
• FlyBaseID: FBgn0028562
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_011964.1
• Gene: HXT5 / 856496
• SGDID: S000001138
• Length: 592
• Species: Saccharomyces cerevisiae
• Alignment Length: 538
• Identity: 128/538 - (23%)
• Similarity: 211/538 - (39%)
• Gaps: 93/538 - (17%)

  Fly     4 VMHVTPPK---------------VNGWTPLLM--LICLTVTLGTTIPVGYFFGVLNAPAEIIKKW 51
            :.|..|||               ....:.||.  :.||.|..|     |:.||           |
Yeast    54 ISHEGPPKDELEELQKEVDKQLEKKSKSDLLFVSVCCLMVAFG-----GFVFG-----------W 102

  Fly    52 CQDILA---NEYDTIVTAGQL---------DILWTSIVSIYLIGGICGSCFSAVLCDKYGRKGCL 104
            ....::   .:.|.|...|..         |:....:|||:.||...|....:.|.|.||||..|
Yeast   103 DTGTISGFVRQTDFIRRFGSTRANGTTYLSDVRTGLMVSIFNIGCAIGGIVLSKLGDMYGRKIGL 167

  Fly   105 VISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIASALIFTAQPMYLLESAPSELSGSVGVFTC 169
            :...|::.: ||:.......|..:..: ||.:.|:....|....||.:.|.:|.:|.|::.....
Yeast   168 MTVVVIYSI-GIIIQIASIDKWYQYFI-GRIISGLGVGGITVLAPMLISEVSPKQLRGTLVSCYQ 230

  Fly   170 IGVTGGILLAQVATLSHLLGSERL-W--PYALSF-YSLLVMASLVLLWWFPESPRWLY-LHKRDS 229
            :.:|.||.|...........|..: |  |..|.| :|:.::..:..:   |||||:|. :.|.:.
Yeast   231 LMITFGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWSIFMIVGMTFV---PESPRYLVEVGKIEE 292

  Fly   230 AASEKALLRLRGRNTEEEVHQELLEMKATLEAKSSSEVSSLCS-------VLRNSELWLPLLLVC 287
            |....|    |...|.|:.....|||:   ..:||.|...|..       |....:::...|:..
Yeast   293 AKRSLA----RANKTTEDSPLVTLEME---NYQSSIEAERLAGSASWGELVTGKPQMFRRTLMGM 350

  Fly   288 SFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTSLLGPLLIRRFPRRPLMMI 352
            ..|:.|||:|.|..|:|..:|....|..|...|.:.||:  .|..::......:.||.||..::.
Yeast   351 MIQSLQQLTGDNYFFYYGTTIFQAVGLEDSFETAIVLGV--VNFVSTFFSLYTVDRFGRRNCLLW 413

  Fly   353 SC--SMCALALLAMSLGLFFL---------ERSESTVLTYFCAAFILTFILGFQLGLGPIAYFIG 406
            .|  .:|...:.| |:|:..|         .:.....:..|...:|..|...:    .|:||.:.
Yeast   414 GCVGMICCYVVYA-SVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTW----APVAYVLI 473

  Fly   407 SELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQSV---WSSFAFIPCMCVCIYCLLLTWRYLP 468
            ||......|..|||:.|..:||..||:....|.:.|.   :..:.|:.||   ::.....:.::|
Yeast   474 SESYPLRVRGKAMSIASACNWIWGFLISFFTPFITSAINFYYGYVFMGCM---VFAYFYVFFFVP 535

  Fly   469 ETRGREPKDVKLLMSQGL 486
            ||:|...::|..:..:.:
Yeast   536 ETKGLTLEEVNEMYEENV 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	MFS_GLUT_Class1_2_like	23..473	CDD:340915	120/487 (25%)
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	122/497 (25%)