DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut2 and HXT4

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_011960.2	Gene:	HXT4 / 856492	SGDID:	S000001134	Length:	576	Species:	Saccharomyces cerevisiae

Alignment Length:	501	Identity:	118/501 - (23%)
Similarity:	215/501 - (42%)	Gaps:	70/501 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAG---QLDIL---------- 72
            :.||.|..|     |:.||                    :||...:|   |.|.:
Yeast    73 ICCLMVAFG-----GFVFG--------------------WDTGTISGFVAQTDFIRRFGMKHHDG 112

  Fly    73 --WTS------IVSIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEM 129
              :.|      ||||:.||...|....|.|.|.||||..|::..|:::: ||:.......|..:.
Yeast   113 TYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYII-GIIIQIASINKWYQY 176

  Fly   130 LMTGRFLGGIASALIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILL---AQVATLSHLLGSE 191
            .: ||.:.|:....|....||.:.|.:|..:.|::.....:.:|.||.|   ....|.::....:
Yeast   177 FI-GRIISGLGVGGIAVLSPMLISEVSPKHIRGTLVSCYQLMITLGIFLGYCTNYGTKTYTNSVQ 240

  Fly   192 RLWPYALSF-YSLLVMASLVLLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEM 255
            ...|..|.| ::|.::..:..:   |||||:|....:...|.....|..:....:..|..|:..:
Yeast   241 WRVPLGLGFAWALFMIGGMTFV---PESPRYLVEVGKIEEAKRSIALSNKVSADDPAVMAEVEVV 302

  Fly   256 KATLEAKSSSEVSSLCSVL-RNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAA 319
            :||:||:..:..:|...:. ..::::..|::....|:.|||:|.|..|:|..::.|..|..|...
Yeast   303 QATVEAEKLAGNASWGEIFSTKTKVFQRLIMGAMIQSLQQLTGDNYFFYYGTTVFTAVGLEDSFE 367

  Fly   320 TWLNLGIGSFNLCTSLLGPLLIRRFPRRP-LMMISCSMCALALLAMSLGLFFL----ERSESTVL 379
            |.:.|||  .|..::.:|..|:.|:.||. |:..:.||.|..::..|:|:..|    :::.|:..
Yeast   368 TSIVLGI--VNFASTFVGIFLVERYGRRRCLLWGAASMTACMVVFASVGVTRLWPNGKKNGSSKG 430

  Fly   380 TYFC-AAFILTFILGFQLGLGPIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQSV 443
            ...| ..|...::..|.....||.:.:.||......:...|::....:||..||:|...|.:...
Yeast   431 AGNCMIVFTCFYLFCFATTWAPIPFVVNSETFPLRVKSKCMAIAQACNWIWGFLIGFFTPFISGA 495

  Fly   444 ---WSSFAFIPCMCVCIYCLLLTWRYLPETRGREPKDVKLLMSQGL 486
               :..:.|:.|:   ::.....:.::|||:|...::|..|..:|:
Yeast   496 IDFYYGYVFMGCL---VFSYFYVFFFVPETKGLTLEEVNTLWEEGV 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	114/484 (24%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	98/403 (24%)
HXT4	NP_011960.2	Sugar_tr	74..534	CDD:395036	116/494 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342865
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2115
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.880