DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut2 and HXT9

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_012316.1	Gene:	HXT9 / 853236	SGDID:	S000003755	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	508	Identity:	113/508 - (22%)
Similarity:	210/508 - (41%)	Gaps:	82/508 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILA---NEYDTIVTAGQLD---------ILW 73
            ::||.:..|     |:.||           |....::   |..|.|...||.:         :..
Yeast    63 ILCLMIAFG-----GFIFG-----------WDTGTISGFVNLSDFIRRFGQKNDKGTYYLSKVRM 111

  Fly    74 TSIVSIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGG 138
            ..||||:.||...|....:.:.|.|||:..|:..:.::|| |||.......|..:..: ||.:.|
Yeast   112 GLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVV-GILIQITSINKWYQYFI-GRIISG 174

  Fly   139 IASALIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERL-----WPYAL 198
            :....|....||.:.|.||.::.|::.....:..|.||.|.....    .|::..     |...|
Yeast   175 LGVGGIAVLSPMLISEVAPKQIRGTLVQLYQLMCTMGIFLGYCTN----YGTKNYHNATQWRVGL 235

  Fly   199 SF---YSLLVMASLVLLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELL-----EM 255
            ..   ::..:::.::.:   |||||:|....:|..|.     |...::.:..|....|     .:
Yeast   236 GLCFAWTTFMVSGMMFV---PESPRYLIEVGKDEEAK-----RSLSKSNKVSVDDPALLAEYDTI 292

  Fly   256 KATLEAKSSSEVSSLCSVL-RNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAA 319
            ||.:|.:..:..:|...:| ..::::..:|:....|:.|||:|.|..|:|..:|..:.|..|...
Yeast   293 KAGIELEKLAGNASWSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGLKDSFQ 357

  Fly   320 TWLNLGIGSFNLCTSLLGPLLIRRFPRRPLMM--ISCSMCALALLAMSLGLFFL----------- 371
            |  ::.||..|..:|.:....|.||.||..::  .:..:|..|:.| |:|:..|
Yeast   358 T--SIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFA-SVGVTKLWPQGSSHQDIT 419

  Fly   372 ERSESTVLTYFCAAFILTFILGFQLGLGPIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMC 436
            .:.....:..|...||.:|...:..|    .|.|.||......:...|::.:..:|:..||:...
Yeast   420 SQGAGNCMIVFTMFFIFSFATTWAGG----CYVIVSETFPLRVKSRGMAIATAANWMWGFLISFF 480

  Fly   437 FPLLQ---SVWSSFAFIPCMCVCIYCLLLTWRYLPETRGREPKDVKLLMSQGL 486
            .|.:.   :.:..:.|:.|:   ::.....:.::|||:|...::|..:..:|:
Yeast   481 TPFITGAINFYYGYVFLGCL---VFAYFYVFFFVPETKGLTLEEVNTMWLEGV 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	110/491 (22%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	95/419 (23%)
HXT9	NP_012316.1	Sugar_tr	64..526	CDD:395036	112/501 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342858
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840