DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sut2 and Slc2a8

DIOPT Version :9

Sequence 1:NP_524732.1 Gene:sut2 / 44269 FlyBaseID:FBgn0028562 Length:491 Species:Drosophila melanogaster
Sequence 2:NP_445946.2 Gene:Slc2a8 / 85256 RGDID:620611 Length:478 Species:Rattus norvegicus


Alignment Length:454 Identity:120/454 - (26%)
Similarity:193/454 - (42%) Gaps:87/454 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 DILANEYDTIVTAGQLDILWTSIVSIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILF 118
            |..|:.:..:||.|.            ..||:.|..    |.|:.|||..|::.:|.||....:.
  Rat    66 DTAASWFGAVVTLGA------------AAGGVLGGW----LLDRAGRKLSLLLCTVPFVTGFAVI 114

  Fly   119 TWCRAAKSLEMLMTGRFLGGIASALIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVAT 183
            |   ||:.:.||:.||.|.|:|..:.....|:|:.|.|...:.|.:|....:.|..|||||.|| 
  Rat   115 T---AARDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVA- 175

  Fly   184 LSHLLGSERLWPYALSFYSLLVMA------SLVLLWWFPESPRWLYLHKRDSAASEKALLRLRGR 242
                       .:.|.:..|.|:.      .|:|:.:.||:||:|....:    .::|:..||..
  Rat   176 -----------GWVLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQ----YQEAMAALRFL 225

  Fly   243 NTEEEVHQELLEMKATLEAKSSSEVSSLCSVLRNSELWLPLLLVCSFQATQQLSGINAIFFYSLS 307
            ...||..:|        ....:.......::||...:..||::.......|||||:|||.||:.:
  Rat   226 WGSEEGWEE--------PPVGAEHQGFQLAMLRRPGVHKPLIIGICLMVFQQLSGVNAIMFYANT 282

  Fly   308 ILTNAGFSDGAATWLNLGIGSFNLCTSLLGPLLIRRFPRRPLMMISCSMCALALLAMSLGLFF-L 371
            |...|.|.|.:...:.:||  ..:..:.:..|::.|..|:.|:.:|..:...::.|  .|.:| |
  Rat   283 IFEEAKFKDSSLASVTVGI--IQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSA--FGTYFKL 343

  Fly   372 ERS----ESTV----------------LTYFCAAFILTFILGFQLGLGPIAYFIGSELLEDSPRP 416
            .:|    .|.|                |.:.....:..||.||.:|.|||.:.:.||:.....:.
  Rat   344 TQSGPSNSSHVGLLVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKG 408

  Fly   417 VAMSMGSLFSWIGNFLVGMCFPLLQSV-------WSSFAFIPCMCVCIYCLLLTWRYLPETRGR 473
            ||..:..|.:|...|||...|..:..:       |.:.||      ||..:|.|..::|||:||
  Rat   409 VATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAF------CILSVLFTLTFVPETKGR 466

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sut2NP_524732.1 Sugar_tr 23..473 CDD:278511 118/452 (26%)
MFS 76..466 CDD:119392 110/423 (26%)
Slc2a8NP_445946.2 Dileucine internalization motif. /evidence=ECO:0000269|PubMed:10671487 12..13
MFS 27..470 CDD:421695 120/454 (26%)
Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166 268..274 5/5 (100%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166337825
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

Return to query results.
Submit another query.