Protein Alignment sut2 and CIN10

DIOPT Version :10

• Sequence 1: NP_524732.1
• Gene: sut2 / 44269
• FlyBaseID: FBgn0028562
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_010675.3
• Gene: CIN10 / 851995
• SGDID: S000002795
• Length: 555
• Species: Saccharomyces cerevisiae
• Alignment Length: 585
• Identity: 124/585 - (21%)
• Similarity: 214/585 - (36%)
• Gaps: 156/585 - (26%)

  Fly     3 VVMHVTPPKVNGWTPLLMLICLTVTL---GTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIV 64
            ::..||....|....|...:....:|   |.||. |..||                    |||.|
Yeast    16 IISQVTSNTANDIEQLPYALTFKTSLIFVGATIG-GLLFG--------------------YDTGV 59

  Fly    65 TAGQL--------------DILWTSIVSIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSG 115
            .:|.|              |:....|.|...:|...||..:..|.|:|||:..|.|...:|:::.
Yeast    60 ISGVLLSLKPEDLSLVVLTDVQKELITSSTSVGSFFGSILAFPLADRYGRRITLAICCSIFILAA 124

  Fly   116 ILFTWCRAAKSLEMLMTGRFLGGIASALIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQ 180
            |   ....|::|..|:.||.|.|||..:.....|::|.|.:||.:.|.:.....|.:|||.|::.
Yeast   125 I---GMAIARTLTFLICGRLLVGIAVGVSAQCVPLFLSEISPSRIRGFMLTLNIIAITGGQLVSY 186

  Fly   181 VATLSHLLGSERLWPYALSFYSLLVMASLVLLWWFPESPRWL-----YLHKRDS------AAS-- 232
            |.. |.:...:..|.|..:..::..:..|.:|.:.||||||.     .|:.|||      .||
Yeast   187 VIA-SLMKEIDNSWRYLFALSAIPAILFLSILDFIPESPRWSISKGDILYTRDSLRMLYPTASTY 250

  Fly   233 ------EKALLRLRGRNTEEEVHQELL------------------------------EMKATLEA 261
                  ::.::.|......|:..:.||                              |..:...:
Yeast   251 HVNSKIKQLIIELDKLRLYEDASEPLLVQSQSVIRYMDSSTSGTLSPPNIKRLSSNTERTSNTMS 315

  Fly   262 KSSSEVSSLCSVLRNSEL--------------WLPLLLVCSFQATQQLSGINAIFFYSLSILTNA 312
            .||:.:|:|.....|..|              ...|::.|.....||::|.||..:|:..|.:
Yeast   316 SSSAYLSALRGPAPNGALASNKKKRHRMEPRTIRALIVGCMLMFFQQITGFNAFMYYAAIIFS-- 378

  Fly   313 GFSDGAATWLNLGIGSFNLCTSLLGPLLIR---------------RFPRRPLMMISCSMCALALL 362
                           .||:...||.|:||.               ...||.:::.:..:..:.||
Yeast   379 ---------------KFNIKNPLLPPILIASTNFIFTFFAMYTMDSLGRRAILLRTILIMTVGLL 428

  Fly   363 AMSLGLFFLERSESTVLTYFCAAFILTFILGFQLGLGPIAYFIGSELLEDSPRPVAMSMGSLFSW 427
            ..|:| |..::....:::      ::.::..:...:|.:.:.. .|.|..:.|....|..:..:|
Yeast   429 LCSVG-FGHDQVNLLLIS------VVIYVAAYASAMGSVPWTC-VEFLPLNRRSFGASCIACTNW 485

  Fly   428 IGNFLVGMCF-PLLQSVWSS-----FAFIPCMCVCIYCLLLTWRYLPETRGREPKDVKLLMSQGL 486
            :.|..|.|.: ..:.::...     |||   ..||.:..:..|  .||.:|...::|..:...|:
Yeast   486 LTNAFVSMTYLSTINTIGDENTMLIFAF---FTVCAWFFVYFW--YPEVKGLSLEEVGRVFDNGI 545

  Fly   487  486
            Yeast   546  545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	MFS_GLUT_Class1_2_like	23..473	CDD:340915	117/550 (21%)
CIN10	NP_010675.3	MFS_HMIT_like	45..528	CDD:340918	114/537 (21%)