DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut2 and INT2

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_174313.1	Gene:	INT2 / 839902	AraportID:	AT1G30220	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	572	Identity:	122/572 - (21%)
Similarity:	231/572 - (40%)	Gaps:	138/572 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 W-TPLLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQLDIL------ 72
            | .|.::.:..:..:|     |..||                    |||.|.:|.|..:
plant    23 WKNPYVLRLAFSAGIG-----GLLFG--------------------YDTGVISGALLYIRDDFKS 62

  Fly    73 -----WTS--IVSIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEML 130
                 |..  |||:.:.|.|.|:.......||.||:..::::..||::..|:..   ||.:..:|
plant    63 VDRNTWLQEMIVSMAVAGAIVGAAIGGWANDKLGRRSAILMADFLFLLGAIIMA---AAPNPSLL 124

  Fly   131 MTGRFLGGIASALIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATL--SHLLGSERL 193
            :.||...|:...:.....|:|:.|::|:::.|::.......:|||..|:.:..|  :.:.|:
plant   125 VVGRVFVGLGVGMASMTAPLYISEASPAKIRGALVSTNGFLITGGQFLSYLINLAFTDVTGT--- 186

  Fly   194 WPYALSFYSLLVMASLVLLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEMKAT 258
            |.:.|....:..:...||::..||||||||...|:..|  ||:  ||...:.|:|.||:..:|.:
plant   187 WRWMLGIAGIPALLQFVLMFTLPESPRWLYRKGREEEA--KAI--LRRIYSAEDVEQEIRALKDS 247

  Fly   259 LEA----KSSSEVSSLCSVLRNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGF-SDGA 318
            :|.    :.|||..::..:.:...:...|:.....|..||..|||.:.:||.:|:..||| |:..
plant   248 VETEILEEGSSEKINMIKLCKAKTVRRGLIAGVGLQVFQQFVGINTVMYYSPTIVQLAGFASNRT 312

  Fly   319 ATWLNLGIGSFNLCTSLLGPLLIRRFPRRPLMMISCSMCALALLAMSLGLFFLERSESTVLTY-- 381
            |..|:|.....|...|::....|.|..|:.|::||. ...:..|.:..|:|:...:.:..::.
plant   313 ALLLSLVTAGLNAFGSIISIYFIDRIGRKKLLIISL-FGVIISLGILTGVFYEAATHAPAISSLE 376

  Fly   382 -----------------------------------FCAA-------------------------- 385
                                               :|::
plant   377 TQRFNNISCPDYKSAMNTNAWDCMTCLKASSPSCGYCSSPIGKEHPGACWISDDSVKDLCHNENR 441

  Fly   386 -------------FIL----TFILGFQLGLGPIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLV 433
                         |.|    .:|:.|..|:|.:.:.:.||:.....|.:...:.:..:||.|.:|
plant   442 LWYTRGCPSNFGWFALLGLGLYIIFFSPGMGTVPWIVNSEIYPLRFRGICGGIAATANWISNLIV 506

  Fly   434 GMCF-PLLQSVWSSFAFIPCMCVCIYCLLLTWRYLPETRGREPKDVKLLMSQ 484
            ...| .|.:::.:|:.|:....:.:..||.....:|||:|...::::.::.:
plant   507 AQSFLSLTEAIGTSWTFLIFGVISVIALLFVMVCVPETKGMPMEEIEKMLER 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	119/550 (22%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	105/477 (22%)
INT2	NP_174313.1	SP	25..552	CDD:273317	121/562 (22%)
INT2	NP_174313.1	MFS	33..541	CDD:119392	116/543 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326501at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920