DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut2 and slc2a1

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001072458.1	Gene:	slc2a1 / 779913	XenbaseID:	XB-GENE-5755357	Length:	492	Species:	Xenopus tropicalis

Alignment Length:	470	Identity:	140/470 - (29%)
Similarity:	247/470 - (52%)	Gaps:	8/470 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TPLLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQLDILWTSIVSIY 80
            |..|||...|..:| ::..||..||:|||.|:|:.:........|:..:....|..||:..|:|:
Frog     8 TARLMLAVCTAVIG-SLQFGYNTGVINAPQEVIEGFYNATWLERYNEPIPESTLTSLWSLSVAIF 71

  Fly    81 LIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIASALIF 145
            .:||:.||....:..:::||:..:::::||..::.||..:.:.|.|.|||:.|||:.|:...|..
Frog    72 SVGGMVGSFSVGLFVNRFGRRNSMLMANVLAFLAAILMGFSKLAVSFEMLIIGRFVVGLYCGLTT 136

  Fly   146 TAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLWPYALSFYSLLVMASLV 210
            ...|||:.|.:|:.|.|::|....:||..|||:||:..|..::|::.|||:.|....:..:...:
Frog   137 GFVPMYVGEVSPTSLRGALGTLHQLGVVVGILIAQIFGLKPIMGNDSLWPFLLGCIFIPAILQCI 201

  Fly   211 LLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEMKATLEAKSSSEVSSLCSVLR 275
            :|.:.|||||:|.:::.:...::..|.:|||..   :|..:|.|||.........:..::..:.|
Frog   202 MLPFCPESPRFLLINRNEEDKAKSVLKKLRGTT---DVSSDLQEMKEESRQMMREKKVTILELFR 263

  Fly   276 NSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTSLLGPLL 340
            :.....|:.:....|.:||||||||:|:||..|...|....  ..:..:|.|..|...:::...:
Frog   264 SPLYRQPMFIAIILQLSQQLSGINAVFYYSTMIFQKAQVEQ--PVYATIGAGIVNTAFTVVSLFV 326

  Fly   341 IRRFPRRPLMMISCSMCALALLAMSLGLFFLERSESTVLTYFCAAFILTFILGFQLGLGPIAYFI 405
            :.|..||.|.:|.....|:..:.|::.|..|:....  ::|.....|..|:..|::|.|||.:||
Frog   327 VERAGRRTLHLIGLGGMAVCAILMTIALALLDSVGG--MSYLSIVAIFGFVAFFEIGPGPIPWFI 389

  Fly   406 GSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQSVWSSFAFIPCMCVCIYCLLLTWRYLPET 470
            .:||....|||.|:::..|.:|..||:|||.|..::.:..::.||....:.:...:.|:..:|||
Frog   390 VAELFSQGPRPAAIAVAGLSNWTSNFIVGMGFQYVEQLCGAYVFIIFTVLLLIFFVFTYFKVPET 454

  Fly   471 RGREPKDVKLLMSQG 485
            :||...::.....||
Frog   455 KGRTFDEIASEFRQG 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	132/449 (29%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	114/389 (29%)
slc2a1	NP_001072458.1	MFS_GLUT_Class1	13..457	CDD:340989	133/451 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	307	1.000	Inparanoid score	I2586
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.050