Protein Alignment sut2 and SLC2A11

DIOPT Version :9

• Sequence 1: NP_524732.1
• Gene: sut2 / 44269
• FlyBaseID: FBgn0028562
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_001269793.1
• Gene: SLC2A11 / 66035
• HGNCID: 14239
• Length: 535
• Species: Homo sapiens
• Alignment Length: 468
• Identity: 143/468 - (30%)
• Similarity: 208/468 - (44%)
• Gaps: 80/468 - (17%)

  Fly    18 LLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQLD-----ILWTSIV 77
            ||:.|| ...:|.|...||...::|||...|:::     .||.....|...|.     ::|:.||
Human    20 LLLTIC-AAGIGGTFQFGYNLSIINAPTLHIQEF-----TNETWQARTGEPLPDHLVLLMWSLIV 78

  Fly    78 SIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIASA 142
            |:|.:||:.|:..:..|....|||..|:::::..|.:.|||.:.|.|.|.||:|.||.|.|:.:.
Human    79 SLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAG 143

  Fly   143 LIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLWPYALSFYSLLV-- 205
            :....|||||.||||.||.|:|.:.:.|....||::.||..|..|||..:.||..|:  |.||
Human   144 VSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLA--SCLVPG 206

  Fly   206 ---MASLVLLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEMKATLEAKSSSEV 267
               :|||.||   |||||:|.:...|:.|...||.||||........:||.|.:|..:.
Human   207 ALQLASLPLL---PESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAACQG------ 262

  Fly   268 SSLCSVLRNSELW--------LPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNL 324
               |...|..||:        :..|:|..  :..:|.|.::::.|:.|:...||..:....:..:
Human   263 ---CRARRPWELFQHRALRRQVTSLVVLG--SAMELCGNDSVYAYASSVFRKAGVPEAKIQYAII 322

  Fly   325 GIGSFNLCTSLL------------GPLLIRRFPRRPLMMISCSMCALALLAMSLGLFFLERSEST 377
            |.||..|.|:::            ..|.....|.||                        |..|.
Human   323 GTGSCELLTAVVSVAGVDEGWGVQAGLTSTSPPPRP------------------------RQSSF 363

  Fly   378 VLT-YFCAAFILTFILGFQLGLGPIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQ 441
            ..| |...|.|..|||.|.:|...:...:.:||.:...||.|..:.....||...|||:.||.:.
Human   364 PWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIM 428

  Fly   442 SVWSSFAF--IPC 452
             |..||..  .||
Human   429 -VLGSFLIRRRPC 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	140/463 (30%)
		MFS	76..466	CDD:119392	126/405 (31%)
SLC2A11	NP_001269793.1	Sugar_tr	22..428	CDD:278511	136/451 (30%)
		MFS	68..>217	CDD:119392	60/153 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144265
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750