Protein Alignment sut2 and SLC2A5

DIOPT Version :10

• Sequence 1: NP_524732.1
• Gene: sut2 / 44269
• FlyBaseID: FBgn0028562
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_003030.1
• Gene: SLC2A5 / 6518
• HGNCID: 11010
• Length: 501
• Species: Homo sapiens
• Alignment Length: 460
• Identity: 140/460 - (30%)
• Similarity: 239/460 - (51%)
• Gaps: 9/460 - (1%)

  Fly    16 TPLLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQLDILWTSIVSIY 80
            |.:|.|..|....|::...||....:|:||.:::::..:.........:....|.:||:..||::
Human    14 TLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTVSMF 78

  Fly    81 LIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIASALIF 145
            ..||..||.....|.:|:||||.|:.:::..:|..||....|.|.|.|:::..|.|.||.:.:..
Human    79 PFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAGVSS 143

  Fly   146 TAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLWPYALSFYSLLVMASLV 210
            ...||||.|.||..|.|::||...:.:|.|||:||:..|.:||.:...||..|....:.....|:
Human   144 NVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTGVPAALQLL 208

  Fly   211 LLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEMKATLEAKSSSEVSSLCSVLR 275
            ||.:||||||:|.:.|:|.||::|||..|||   .:.|.:|:.|::...||:.::...|:..:.|
Human   209 LLPFFPESPRYLLIQKKDEAAAKKALQTLRG---WDSVDREVAEIRQEDEAEKAAGFISVLKLFR 270

  Fly   276 NSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTSLLGPLL 340
            ...|...||.:......|||||:|||::|:..|..:||..:....::..|.|:.|:..:.....:
Human   271 MRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFV 335

  Fly   341 IRRFPRRPLMMISCSMCALALLAMSLGLFFLERSESTV--LTYFCAAFILTFILGFQLGLGPIAY 403
            :....||.|:::..|:|.:|...::..|..    :.||  :.|.....::::::|..||..||..
Human   336 VELLGRRLLLLLGFSICLIACCVLTAALAL----QDTVSWMPYISIVCVISYVIGHALGPSPIPA 396

  Fly   404 FIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQSVWSSFAFIPCMCVCIYCLLLTWRYLP 468
            .:.:|:...|.||.|..:|....|:.||.||:.||.:|.....::||....:|:...:..:..:|
Human   397 LLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVP 461

  Fly   469 ETRGR 473
            ||:.:
Human   462 ETKAK 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	MFS_GLUT_Class1_2_like	23..473	CDD:340915	137/451 (30%)
SLC2A5	NP_003030.1	MFS_GLUT_Class2	23..471	CDD:340990	136/451 (30%)