Protein Alignment sut2 and SLC2A2

DIOPT Version :10

• Sequence 1: NP_524732.1
• Gene: sut2 / 44269
• FlyBaseID: FBgn0028562
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_000331.1
• Gene: SLC2A2 / 6514
• HGNCID: 11006
• Length: 524
• Species: Homo sapiens
• Alignment Length: 506
• Identity: 144/506 - (28%)
• Similarity: 252/506 - (49%)
• Gaps: 45/506 - (8%)

  Fly     7 VTPPKVNGWTPLLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILA---------NEY-- 60
            :|..||.|   .|:...:|..|| :...||..||:|||.::|....:.:|.         |.|
Human     1 MTEDKVTG---TLVFTVITAVLG-SFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVI 61

  Fly    61 -----------------------DTIVTAGQLDILWTSIVSIYLIGGICGSCFSAVLCDKYGRKG 102
                                   :|:..|..:.:||:..||.:.:||:..|.|...|.|..||..
Human    62 NSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGRIK 126

  Fly   103 CLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIASALIFTAQPMYLLESAPSELSGSVGVF 167
            .::::::|.:|..:|..:.:...|..:::.||.:.|:...||....|||:.|.||:.|.|::|.|
Human   127 AMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTF 191

  Fly   168 TCIGVTGGILLAQVATLSHLLGSERLWPYALSFYSLLVMASLVLLWWFPESPRWLYLHKRDSAAS 232
            ..:.:..|||::|:..|..:||:..||...|....:..:...:||::.|||||:||:...:...:
Human   192 HQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKA 256

  Fly   233 EKALLRLRGRNTEEEVHQELLEMKATLEAKSSSEVSSLCSVLRNSELWLPLLLVCSFQATQQLSG 297
            :::|.||||   .::|.:::.||:...|..||.:..|:..:..||....|:|:.......||.||
Human   257 KQSLKRLRG---YDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSG 318

  Fly   298 INAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTSLLGPLLIRRFPRRPLMMISCSMCALALL 362
            ||.||:||.||...||.|  ...:..:|:|:.|:..:.:...|:.:..||.|.:|..|...:..:
Human   319 INGIFYYSTSIFQTAGIS--KPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAI 381

  Fly   363 AMSLGLFFLERSESTVLTYFCAAFILTFILGFQLGLGPIAYFIGSELLEDSPRPVAMSMGSLFSW 427
            .||:||..|  ::.:.::|.....|..|:..|::|.|||.:|:.:|.....|||.|:::.:..:|
Human   382 FMSVGLVLL--NKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNW 444

  Fly   428 IGNFLVGMCFPLLQSVWSSFAFIPCMCVCIYCLLLTWRYLPETRGREPKDV 478
            ..||:|.:||..:......:.|.....|.:...|.|:..:|||:|:..:::
Human   445 TCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVPETKGKSFEEI 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	MFS_GLUT_Class1_2_like	23..473	CDD:340915	138/483 (29%)
SLC2A2	NP_000331.1	MFS_GLUT_Class1	12..490	CDD:340989	138/485 (28%)