Protein Alignment sut2 and SLC2A1

DIOPT Version :9

• Sequence 1: NP_524732.1
• Gene: sut2 / 44269
• FlyBaseID: FBgn0028562
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_006507.2
• Gene: SLC2A1 / 6513
• HGNCID: 11005
• Length: 492
• Species: Homo sapiens
• Alignment Length: 480
• Identity: 147/480 - (30%)
• Similarity: 254/480 - (52%)
• Gaps: 8/480 - (1%)

  Fly    10 PKVNGWTPLLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQLDILWT 74
            |.....|..|||......|| ::..||..||:|||.::|:::......:.|...:....|..||:
Human     3 PSSKKLTGRLMLAVGGAVLG-SLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWS 66

  Fly    75 SIVSIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGI 139
            ..|:|:.:||:.||....:..:::||:..:::.::|..||.:|..:.:..||.|||:.|||:.|:
Human    67 LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGV 131

  Fly   140 ASALIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLWPYALSFYSLL 204
            ...|.....|||:.|.:|:.|.|::|....:|:..|||:|||..|..::|::.|||..||...:.
Human   132 YCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIP 196

  Fly   205 VMASLVLLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEMKATLEAKSSSEVSS 269
            .:...::|.:.|||||:|.:::.:...::..|.:|||  |.:..| :|.|||.........:..:
Human   197 ALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRG--TADVTH-DLQEMKEESRQMMREKKVT 258

  Fly   270 LCSVLRNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTS 334
            :..:.|:.....|:|:....|.:||||||||:|:||.||...||...  ..:..:|.|..|...:
Human   259 ILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQ--PVYATIGSGIVNTAFT 321

  Fly   335 LLGPLLIRRFPRRPLMMISCSMCALALLAMSLGLFFLERSESTVLTYFCAAFILTFILGFQLGLG 399
            ::...::.|..||.|.:|..:..|...:.|::.|..||  :...::|.....|..|:..|::|.|
Human   322 VVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLE--QLPWMSYLSIVAIFGFVAFFEVGPG 384

  Fly   400 PIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQSVWSSFAFIPCMCVCIYCLLLTW 464
            ||.:||.:||....|||.|:::....:|..||:|||||..::.:...:.||....:.:...:.|:
Human   385 PIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTY 449

  Fly   465 RYLPETRGREPKDVKLLMSQGLSSK 489
            ..:|||:||...::.....||.:|:
Human   450 FKVPETKGRTFDEIASGFRQGGASQ 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	137/449 (31%)
		MFS	76..466	CDD:119392	120/389 (31%)
SLC2A1	NP_006507.2	MFS_GLUT_Class1	14..458	CDD:340989	138/451 (31%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:24847886	282..288		5/5 (100%)
		Disordered. /evidence=ECO:0000305|PubMed:30197081	468..492		3/7 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144181
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	319	0.197	Inparanoid score	I2535
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.900