DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut2 and slc2a1a

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001034897.1	Gene:	slc2a1a / 555778	ZFINID:	ZDB-GENE-030131-3158	Length:	488	Species:	Danio rerio

Alignment Length:	476	Identity:	145/476 - (30%)
Similarity:	258/476 - (54%)	Gaps:	9/476 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TPLLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQLDILWTSIVSIY 80
            ||.||:...|..:| ::..||..||:|||.:||:.:..:...|.|...:....|..||:..|:|:
Zfish     9 TPQLMMAVGTAVIG-SLQFGYNTGVINAPQKIIEGFYNETWHNRYSEYIPPTTLTTLWSVSVAIF 72

  Fly    81 LIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIASALIF 145
            .:|||.||....:..:::||:..::|:::|..::.....:.:.|:|.|||:.|||:.|:.|.|..
Zfish    73 SVGGILGSFSVGLFVNRFGRRNSMLIANILAFIAAAFMGFSKLAESWEMLIIGRFIVGLYSGLST 137

  Fly   146 TAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLWPYALSFYSLLVMASLV 210
            ...|||:.|.||:.|.|::|....:|:..|||:||:..:..::||..|||:.|.|..:..:....
Zfish   138 GFVPMYVGEIAPTSLRGALGTLHQLGIVIGILMAQIFGIKEIMGSPTLWPFMLGFTFIPAVLQCA 202

  Fly   211 LLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEMKATLEAKSSSEVSSLCSVLR 275
            ||.:.|||||:|.:::.:.|.::..|.:|||   .::|..::.||:.........:..::..:.|
Zfish   203 LLPFCPESPRYLLINQNEEAKAKSVLKKLRG---TDDVGADMQEMRDESRQMMREKTVTIPELFR 264

  Fly   276 NSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTSLLGPLL 340
            :|....|:.:....|.:||.|||||:|:||..|...||.|:  ..:..:|.|:.|...:::...:
Zfish   265 SSLYRQPIFIAIMLQLSQQFSGINAVFYYSTGIFEKAGVSE--PVYATIGAGAVNTAFTVVSLFI 327

  Fly   341 IRRFPRRPLMMISCSMCALALLAMSLGLFFLERSESTVLTYFCAAFILTFILGFQLGLGPIAYFI 405
            :.|..||.|.::.....|::.:.|::.:..|.:.|  .::|.....|.:|:..|::|.|||.:||
Zfish   328 VERVGRRSLHLVGLMGMAVSSVLMTIAMALLTKVE--WMSYVSIVAIFSFVAFFEIGPGPIPWFI 390

  Fly   406 GSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQSVWSSFAFIPCMCVCIYCLLLTWRYLPET 470
            .:||....|||.|.::....:|..||||||||..::.:...:.||....:.:...:.|:..:|||
Zfish   391 VAELFSQGPRPSAFAVAGFSNWFANFLVGMCFQYVEELTGPYVFIIFTVLLLIFFVFTYFKVPET 455

  Fly   471 RGREPKDVKLLMSQGLSSKLN 491
            :||..:::......| :.|.|
Zfish   456 KGRSFEEITASFRTG-ADKYN 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	136/449 (30%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	117/389 (30%)
slc2a1a	NP_001034897.1	Sugar_tr	18..467	CDD:278511	138/456 (30%)
slc2a1a	NP_001034897.1	MFS	62..450	CDD:119392	119/394 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577178
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2574
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.900