DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut2 and Slc2a9

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001178480.1	Gene:	Slc2a9 / 501925	RGDID:	1597012	Length:	545	Species:	Rattus norvegicus

Alignment Length:	487	Identity:	148/487 - (30%)
Similarity:	236/487 - (48%)	Gaps:	21/487 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PPKVNGWTPLLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQLDILW 73
            |.:...|:..|::..|....|::...||...|:|||...||.:..:.....:...:....|.:||
  Rat    34 PRRTKNWSCSLIVAALVGAFGSSFLYGYNLSVVNAPTPYIKAFYNETWYRRHGQPIDPDTLTLLW 98

  Fly    74 TSIVSIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGG 138
            :..|||:.|||:.|:....::....|||..|::::...:.:.:|......|.:.|||:.|||:.|
  Rat    99 SVTVSIFAIGGLVGTLMVKMIGKFLGRKYTLLVNNGFAISAALLMACSLQAGTFEMLIVGRFIMG 163

  Fly   139 IASALIFTAQPMYLLESAPSELSGSVG----VFTCIGVTGGILLAQVATLSHLLGSERLWPYALS 199
            :...:..:|.||||.|.:|.|:.||:|    :|.||||..|.||.    |..|||.||.|||...
  Rat   164 VDGGIALSALPMYLNEISPKEIRGSLGQVTAIFICIGVFSGQLLG----LPELLGKERTWPYLFG 224

  Fly   200 FYSLLVMASLVLLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEMKATLEAKSS 264
            ...:..:|.|..|.:.|||||:|...|.|.|.:.||.....|:   .:|.|||.|..|....:.:
  Rat   225 VIIVPALAQLASLPFLPESPRYLLFEKHDEAGATKAFQTFLGK---ADVSQELEEALAESRVQRN 286

  Fly   265 SEVSSLCSVLRNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSF 329
            ..:.|:..:||...:...::.|....|:.||.|:|||:||:.||...||.......::.|..|..
  Rat   287 LRLVSVFELLRAPFVRWQVITVVITMASYQLCGLNAIWFYTNSIFGKAGVPQDKIPYITLSTGGI 351

  Fly   330 NLCTSLLGPLLIRRFPRRPLMMISCSMCAL--ALLAMSLGLFFLERSESTVLTYFCAAFILTFIL 392
            ....::...|:|.|..||||::....:.||  .:|.::|.|    :.::..:.|.....||..|.
  Rat   352 ETLAAIFSGLVIERLGRRPLLIGGFGLMALFFGMLTVTLTL----QDQAPWIPYLSIVCILAIIA 412

  Fly   393 GFQLGLGPIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQSVWSSFAFIPCMCVCI 457
            .|..|.|.|.:.:..|..:.|.||.|..:....:|:.||:||:.||.:|....|:.|:....:||
  Rat   413 SFCSGPGGIPFILTGEFFQQSERPAAFIIAGTVNWLSNFVVGLLFPFIQKSLESYCFLVFATICI 477

  Fly   458 YCLLLTWRYLPETRGREPKDVKLLMSQGLSSK 489
            ...:..:..||||:.|...::    ||..:.:
  Rat   478 AGAIYFYFVLPETKNRTHAEI----SQAFAKR 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	142/455 (31%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	125/395 (32%)
Slc2a9	NP_001178480.1	Sugar_tr	47..502	CDD:278511	145/469 (31%)
Slc2a9	NP_001178480.1	MFS	49..486	CDD:119392	138/447 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338001
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	0.113	Inparanoid score	I2429
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.800