DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut2 and slc2a5

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001008187.1	Gene:	slc2a5 / 493549	XenbaseID:	XB-GENE-494009	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	485	Identity:	141/485 - (29%)
Similarity:	252/485 - (51%)	Gaps:	21/485 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TPLLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQLDILWTSIVSIY 80
            |..|:|:.|..|.|::...||....:|:|:..:|.:..........:.:....|.:||:..||:|
Frog    18 TATLILVTLVATFGSSFQYGYNVASVNSPSPFMKDFYNSTNIERVGSPLEDAFLTLLWSLTVSLY 82

  Fly    81 LIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIASALIF 145
            .:||..||.....|..|.||||.|:.:::..::..||......||:.|:::..|...|:.:.|..
Frog    83 PLGGFFGSLLVGPLVSKLGRKGTLLFNNIFSIIPAILMGTSVVAKTFEVIIASRLFVGVCAGLSS 147

  Fly   146 TAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLWPYALSFYSLLVMASLV 210
            ...|||:.|.:|..|.|::|:...:.:|.|||:||:..:.::||:...||..|:...:..:..|.
Frog   148 NVVPMYVGEMSPKNLRGAIGIMPQLMITVGILMAQIFGIRYILGNTEGWPILLALTGIPAVLELA 212

  Fly   211 LLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEM---KATLEAKSSSEVSSLCS 272
            .|.:||||||:..|||.:...::|||.||||   .|:|..|:.||   ..:.:|:....|.:||:
Frog   213 FLPFFPESPRYTLLHKGNEDKAKKALQRLRG---WEDVDSEIKEMYQEDQSEKAEGQLSVRNLCT 274

  Fly   273 V--LRNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTSL 335
            .  ||    | .|:.:......||||||||:::|:.||..:||..:....::.:..||.|:..:|
Frog   275 FRPLR----W-QLISIIVMNMGQQLSGINAVYYYADSIYKSAGVKEETIQYVTVATGSVNVLMTL 334

  Fly   336 LGPLLIRRFPRRPLMMISCSMCALALLAMSLGLFFLERSESTV--LTYFCAAFILTFILGFQLGL 398
            ....::..:.||.|::.....|.::.:.:::.|.:    ::||  :.|...|.|:.:::|..:|.
Frog   335 AAVFIVDSWGRRVLLLSGFGTCCISCVVLTIALVY----QTTVSWMPYLSIACIIIYVIGHAIGP 395

  Fly   399 GPIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQSVWSSFAFIPCMCVCIYCLLLT 463
            .||.|.|.:|:...:.||.|..:.....|:.||::|:.|..|.:...::.||....:|:...:..
Frog   396 SPIPYVITTEMFRQASRPAAFMIAGSVHWLSNFIIGLIFEFLMNGLGAYCFILFAAICLATFIFI 460

  Fly   464 WRYLPETRGREPKDVKLLMSQ--GLSSKLN 491
            :..:|||:|:...:|..||::  ||...::
Frog   461 YIVVPETKGKTFLEVSQLMAKRNGLEETVD 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	132/456 (29%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	118/396 (30%)
slc2a5	NP_001008187.1	MFS_GLUT_Class2	24..475	CDD:340990	133/462 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	307	1.000	Inparanoid score	I2586
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.970