DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut2 and Slc2a10

DIOPT Version :9

Sequence 1:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001102433.1	Gene:	Slc2a10 / 366251	RGDID:	1306552	Length:	536	Species:	Rattus norvegicus

Alignment Length:	553	Identity:	110/553 - (19%)
Similarity:	213/553 - (38%)	Gaps:	136/553 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GWTPLLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQLDILWTSIVS 78
            |..|.::.:|.:|:|...:..||...|::..          :|..:.|..::..:.::|    |.
  Rat     2 GLGPTVLPLCASVSLLGGLTFGYELAVISGA----------LLPLQLDFRLSCLEQELL----VG 52

  Fly    79 IYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIASAL 143
            ..|:|....|.....|.|.|||:..::.|:|:.:...::.   ..|.||..|:.||...|.|.:|
  Rat    53 SLLLGAFLASLVGGFLIDCYGRRRAILGSNVVLLAGSLIL---GLAGSLPWLLLGRSSVGFAISL 114

  Fly   144 IFTAQPMYLLESAPSELSG--SVGVFTC---IGVTGGILLAQVATLSHLL-GSERLWPYALSFYS 202
            ...|..:|:     |||.|  ..||...   :|:|.|||.:.  .|:::| ||...|.:...:.:
  Rat   115 SSMACCIYV-----SELVGPRQRGVLVSLYEVGITVGILFSY--GLNYVLAGSPWGWRHMFGWAA 172

  Fly   203 LLVMASLVLLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEE----EVHQELLEMKATLEAKS 263
            ...:...:.|::.|..        .:..|:.:.|:.|:|..|.:    :.....|::....:...
  Rat   173 APALLQSLSLFFLPAG--------AEGTAARQDLIPLQGGETSKLGLVKAQYTFLDLFRAQDGMW 229

  Fly   264 SSEVSSLCSVLRNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWL-NLGIG 327
            |..|..|..||                 .|||:|...:.:|:.:|..:.||..|::..| ::|:|
  Rat   230 SRTVVGLGLVL-----------------FQQLTGQPNVLYYASTIFRSVGFHGGSSAVLASVGLG 277

  Fly   328 SFNLCTSLLGPLLIRRFPRRPLMMISCSMCALALLAMSLGLFFL--------------------- 371
            :..:..:|:...|:.|..||.|::..|::.||::..:.|..|.:
  Rat   278 TVKVVATLIATGLVDRVGRRALLLSGCALMALSVSGIGLVSFAVSLDSGPSCLATSNTSQQVDLP 342

  Fly   372 -----------------------------ER-------------------------SESTVLTYF 382
                                         ||                         .|.|:|.:.
  Rat   343 QTPGLLVRTSLPPVLHTSGDQGQPVRSVTERPIHPVITASLGPALNIDSSVPTSPIPEHTLLCWS 407

  Fly   383 CAAFILTFILGFQLGLGPIAYFIGSELLEDSPRPVAMSMGSLFSWIGNFLVGMCF-PLLQSVWSS 446
            ....::.::..|..|.||:.:.:.||:.....|..|.:..|.|:|..|..:.:.| .|:.::..:
  Rat   408 ALVCMMVYVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCSSFNWAANLFISLSFLDLIGAIGLA 472

  Fly   447 FAFIPCMCVCIYCLLLTWRYLPETRGREPKDVK 479
            :.|:......:..|...:..:|||:|:...:::
  Rat   473 WTFLLYGLTAVLGLAFIYLLVPETKGQSLAEIE 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	107/536 (20%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	95/476 (20%)
Slc2a10	NP_001102433.1	Sugar_tr	11..508	CDD:278511	108/544 (20%)
Slc2a10	NP_001102433.1	MFS	14..>330	CDD:119392	82/364 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337909
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326501at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940